Ruthenium Catalyzed meta-Carboxylation

Research output: Contribution to journalArticle

Abstract

The meta-carboxylation of arenes containing pyridine and other azine directing groups is reported. Using carbon tetrabromide as the C1 source, ruthenium(III) trichloride catalysis enables functionalization of the arene meta C-H position, affording carboxy methyl ester products after in situ reaction with methanol.

Bibliographical metadata

Original languageEnglish
JournalOrganic Letters
Early online date23 Nov 2017
DOIs
Publication statusPublished - 2017