Rotary and linear molecular motors driven by pulses of a chemical fuel

Research output: Contribution to journalArticle

  • External authors:
  • Sundus Erbas-Cakmak
  • Stephen D.P. Fielden
  • Ulvi Karaca
  • Charlie T. McTernan
  • Daniel J. Tetlow
  • Miriam R. Wilson


Many biomolecular motors catalyze the hydrolysis of chemical fuels, such as adenosine triphosphate, and use the energy released to direct motion through information ratchet mechanisms. Here we describe chemically-driven artificial rotary and linear molecular motors that operate through a fundamentally different type of mechanism. The directional rotation of [2]- and [3]catenane rotary molecular motors and the transport of substrates away from equilibrium by a linear molecular pump are induced by acid-base oscillations. The changes simultaneously switch the binding site affinities and the labilities of barriers on the track, creating an energy ratchet. The linear and rotary molecular motors are driven by aliquots of a chemical fuel, trichloroacetic acid. A single fuel pulse generates 360° unidirectional rotation of up to 87% of crown ethers in a [2]catenane rotary motor.

Bibliographical metadata

Original languageEnglish
Pages (from-to)340-343
Number of pages4
Issue number6361
Early online date20 Oct 2017
Publication statusPublished - 2017

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