Risk biomarkers enable precision in public health

Research output: Contribution to journalReview articlepeer-review

Abstract

Abstract
Precision Medicine uses biomarkers to diagnose disease. However they can also be used to measure risk of disease. Thus biomarkers herald a new addition to public health - Precision Public Health. We examine the implications.
Risk biomarkers are identified by analysing population cohorts. They constitute risk factors in mathematical “Disease Risk Models”. The risk may be fixed as in a genetic biomarker or variable as in some protein biomarkers. They help monitor current risk of disease in an individual, thereby aiding efforts to reduce risk.
In the UK, the NHS Health Check system is a universal system for assessing risk and for risk-reduction. The system can now make use of modern biomarkers once appropriate infrastructure and governance are in place.

Bibliographical metadata

Original languageEnglish
JournalPersonalized Medicine
Early online date29 Jun 2018
DOIs
Publication statusPublished - 29 Jun 2018