Remote conformational responses to enantiomeric excess in carboxylate-binding dynamic foldamers

Research output: Contribution to journalArticle

  • External authors:
  • Natasha Eccles
  • Bryden Le Bailly
  • Flavio Della Sala
  • Inigo Vitorica-yrzebal
  • Jonathan Clayden


A crystallographically characterised zinc(II)-capped foldamer can sense the enantiomeric excess of scalemic carboxylate solutions, including those produced by enantioselective organocatalysis, and can relay this input signal along the foldamer body to a remote glycinamide group, which then provides an NMR spectroscopic output.

Bibliographical metadata

Original languageEnglish
JournalChemical Communications
Early online date8 Jul 2019
Publication statusPublished - 2019