This essay provides insights into the reasons why efforts to integrate micro and macro perspectives continue to face challenges. We incorporate the reflections of several experienced researchers on the persistence of the micro-macro divide, organize those reflections into broad themes, and discuss associated insights, implications and challenges. We note that while immense challenges remain, efforts should continue as greater integration can improve the position of our field in the broader social sciences and lead to substantial contributions. Several suggestions are provided to help this research agenda move forward. Specifically, we advocate developing new process-oriented theories and methods as well as adopting broader and more inclusive researcher identities, encouraging “intellectual generosity”, and acknowledging that for some research, integration is neither necessary nor desirable.