Reduction of selenoamides to amines using SmI2-H2O

Research output: Contribution to journalArticle

  • Authors:
  • Samuel Thurow
  • Eder J Lenardão
  • Xavier Just-Baringo
  • David Procter


Selenoamides are selectively reduced to amines by SmI2 with H2O. The process is general for primary, secondary and tertiary aryl and alkyl selenoamide substrates and selectively delivers amine products. The reduction proceeds under mild conditions using SmI2 activated by straightforward addition of H2O, and does not require an additional Lewis base additive.

Bibliographical metadata

Original languageEnglish
Pages (from-to)50-53
Number of pages4
JournalOrganic Letters
Issue number1
Early online date9 Dec 2016
StatePublished - 6 Jan 2017