Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometryCitation formats

  • External authors:
  • Cunyu Yan
  • Jason Schmidberger
  • Shaneela Hussain

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Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometry. / Yan, Cunyu; Schmidberger, Jason; Parmeggiani, Fabio; Hussain, Shaneela; Turner, Nicholas; Flitsch, Sabine; Barran, Perdita.

In: Analyst, 2016.

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@article{1a35a71a03f94cc396c4c43174fac140,
title = "Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometry",
abstract = "The combination of stable isotope labelling with direct infusion ion mobility mass spectrometry (IM-MS) enabled qualitative and quantitative monitoring of biocatalytic reactions with reduced analysis times, enhanced sensitivity and μL-level assay volumes. The new approach was demonstrated by applying to both lipase and monooxygenase enzymes, including multi-substrate screening.",
author = "Cunyu Yan and Jason Schmidberger and Fabio Parmeggiani and Shaneela Hussain and Nicholas Turner and Sabine Flitsch and Perdita Barran",
year = "2016",
doi = "10.1039/C6AN00617E",
language = "English",
journal = "The Analyst",
issn = "0003-2654",
publisher = "Royal Society of Chemistry",

}

RIS

TY - JOUR

T1 - Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometry

AU - Yan, Cunyu

AU - Schmidberger, Jason

AU - Parmeggiani, Fabio

AU - Hussain, Shaneela

AU - Turner, Nicholas

AU - Flitsch, Sabine

AU - Barran, Perdita

PY - 2016

Y1 - 2016

N2 - The combination of stable isotope labelling with direct infusion ion mobility mass spectrometry (IM-MS) enabled qualitative and quantitative monitoring of biocatalytic reactions with reduced analysis times, enhanced sensitivity and μL-level assay volumes. The new approach was demonstrated by applying to both lipase and monooxygenase enzymes, including multi-substrate screening.

AB - The combination of stable isotope labelling with direct infusion ion mobility mass spectrometry (IM-MS) enabled qualitative and quantitative monitoring of biocatalytic reactions with reduced analysis times, enhanced sensitivity and μL-level assay volumes. The new approach was demonstrated by applying to both lipase and monooxygenase enzymes, including multi-substrate screening.

U2 - 10.1039/C6AN00617E

DO - 10.1039/C6AN00617E

M3 - Article

JO - The Analyst

JF - The Analyst

SN - 0003-2654

ER -