Rapid and sensitive monitoring of biocatalytic reactions using ion mobility mass spectrometry

Research output: Research - peer-reviewArticle

  • External authors:
  • Cunyu Yan
  • Jason Schmidberger
  • Shaneela Hussain


The combination of stable isotope labelling with direct infusion ion mobility mass spectrometry (IM-MS) enabled qualitative and quantitative monitoring of biocatalytic reactions with reduced analysis times, enhanced sensitivity and μL-level assay volumes. The new approach was demonstrated by applying to both lipase and monooxygenase enzymes, including multi-substrate screening.

Bibliographical metadata

Original languageEnglish
Early online date16 Mar 2016
StatePublished - 2016