Radiation and the genome: From risks to opportunities for therapeutic exploitationCitation formats

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Radiation and the genome: From risks to opportunities for therapeutic exploitation. / Robson, T.; West, C.

In: British Journal of Radiology, Vol. 83, No. 992, 08.2010, p. 635-637.

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Robson, T. ; West, C. / Radiation and the genome: From risks to opportunities for therapeutic exploitation. In: British Journal of Radiology. 2010 ; Vol. 83, No. 992. pp. 635-637.

Bibtex

@article{f10b6f593cf6420dbbd99fdac62e23e7,
title = "Radiation and the genome: From risks to opportunities for therapeutic exploitation",
abstract = "On 1 December 2009, the Radiation and Cancer Biology Committee of the British Institute of Radiology (BIR) held a one-day conference on the theme of radiation and the genome. Talks covered genomic instability (its importance for radiation-induced carcinogenesis and potential for exploitation in the development of novel chemoradiotherapy combinations) and the prospects of exploiting knowledge of the genome to understand how individual genetic variation can impact on a patient's likelihood of developing toxicity following radiotherapy. The meeting also provided an overview of stem cell biology and its relevance for radiotherapy in terms of both tumour (somatic) and normal tissue (germline) sensitivity to radiation. Moreover, the possibility of manipulating stem cells to reduce radiation-induced normal tissue damage was considered. {\circledC} 2010 The British Institute of Radiology.",
author = "T. Robson and C. West",
year = "2010",
month = "8",
doi = "10.1259/bjr/31552255",
language = "English",
volume = "83",
pages = "635--637",
journal = "British Journal of Radiology",
issn = "0007-1285",
publisher = "British Institute of Radiology",
number = "992",

}

RIS

TY - JOUR

T1 - Radiation and the genome: From risks to opportunities for therapeutic exploitation

AU - Robson, T.

AU - West, C.

PY - 2010/8

Y1 - 2010/8

N2 - On 1 December 2009, the Radiation and Cancer Biology Committee of the British Institute of Radiology (BIR) held a one-day conference on the theme of radiation and the genome. Talks covered genomic instability (its importance for radiation-induced carcinogenesis and potential for exploitation in the development of novel chemoradiotherapy combinations) and the prospects of exploiting knowledge of the genome to understand how individual genetic variation can impact on a patient's likelihood of developing toxicity following radiotherapy. The meeting also provided an overview of stem cell biology and its relevance for radiotherapy in terms of both tumour (somatic) and normal tissue (germline) sensitivity to radiation. Moreover, the possibility of manipulating stem cells to reduce radiation-induced normal tissue damage was considered. © 2010 The British Institute of Radiology.

AB - On 1 December 2009, the Radiation and Cancer Biology Committee of the British Institute of Radiology (BIR) held a one-day conference on the theme of radiation and the genome. Talks covered genomic instability (its importance for radiation-induced carcinogenesis and potential for exploitation in the development of novel chemoradiotherapy combinations) and the prospects of exploiting knowledge of the genome to understand how individual genetic variation can impact on a patient's likelihood of developing toxicity following radiotherapy. The meeting also provided an overview of stem cell biology and its relevance for radiotherapy in terms of both tumour (somatic) and normal tissue (germline) sensitivity to radiation. Moreover, the possibility of manipulating stem cells to reduce radiation-induced normal tissue damage was considered. © 2010 The British Institute of Radiology.

U2 - 10.1259/bjr/31552255

DO - 10.1259/bjr/31552255

M3 - Article

VL - 83

SP - 635

EP - 637

JO - British Journal of Radiology

JF - British Journal of Radiology

SN - 0007-1285

IS - 992

ER -