Quantification of local rectal wall displacements by virtual rectum unfolding.

Research output: Contribution to journalArticle

  • External authors:
  • Mischa S Hoogeman
  • Marcel van Herk
  • Josien de Bois
  • Pietje Muller-Timmermans
  • Peter C M Koper
  • Joos V Lebesque


BACKGROUND AND PURPOSE: To develop a method to project surface elements of a bent tubular organ, e.g. the rectum, in order to create a two-dimensional (2D) map and to use this method to quantify on a local scale shape and position variations of the rectum. PATIENTS AND METHODS: For this study we used data of 19 patients, who each received a planning CT scan and 9-13 repeat CT scans that were considered representative for the radiotherapy course. We combined maps from multiple CT scans of the same patient to quantify local rectal wall displacements. To make a map we first computed a central axis through the rectum and divided it into segments of equal length assuming that the length of these segments was invariant under rectum shape and position changes. Next, we constructed for each segment a planar cross section through the rectum, which was oriented orthogonally to that segment. The amount of rectal wall tissue was assumed to be constant in all orthogonal cross sections throughout the entire rectum. We unfolded the cross-sected rectal wall at the dorsal side and projected either the associated dose or the coordinates onto the map. RESULTS: The largest variation in the position of the rectal wall during the treatment course occurred at the upper anterior, left and right side (1 SD=5-7 mm). Near the anus the variation was

Bibliographical metadata

Original languageEnglish
JournalRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Issue number1
Publication statusPublished - Jan 2004