Pupil responses to hidden photoreceptor–specific modulations in moviesCitation formats

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Pupil responses to hidden photoreceptor–specific modulations in movies. / Spitschan, Manuel; Gardasevic, Marina; Martial, Franck P.; Lucas, Robert J.; Allen, Annette E.

In: PLoS ONE, Vol. 14, No. 5, e0216307, 09.05.2019.

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@article{3ca3155f79a447b5a3e80da961dff130,
title = "Pupil responses to hidden photoreceptor–specific modulations in movies",
abstract = "Under typical daytime light levels, the human pupillary light response (PLR) is driven by the activity of the L, M, and S cones, and melanopsin expressed in the so-called intrinsically photosensitive retinal ganglion cells (ipRGCs). However, the importance of each of these photoreceptive mechanisms in defining pupil size under real-world viewing conditions remains to be established. To address this question, we embedded photoreceptor-specific modulations in a movie displayed using a novel projector-based five-primary spatial stimulation system, which allowed for the precise control of photoreceptor activations in time and space. We measured the pupillary light response in eleven observers, who viewed short cartoon movies which contained hidden low-frequency (0.25 Hz) silent-substitution modulations of the L, M and S cones (no stimulation of melanopsin), melanopsin (no stimulation of L, M and S cones), both L, M, and S cones and melanopsin or no modulation at all. We find that all photoreceptors active at photopic light levels regulate pupil size under this condition. Our data imply that embedding modulations in photoreceptor contrast could provide a method to manipulate key adaptive aspects of the human visual system in everyday, real-world activities such as watching a movie.",
author = "Manuel Spitschan and Marina Gardasevic and Martial, {Franck P.} and Lucas, {Robert J.} and Allen, {Annette E.}",
year = "2019",
month = may,
day = "9",
doi = "10.1371/journal.pone.0216307",
language = "English",
volume = "14",
journal = "PL o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "5",

}

RIS

TY - JOUR

T1 - Pupil responses to hidden photoreceptor–specific modulations in movies

AU - Spitschan, Manuel

AU - Gardasevic, Marina

AU - Martial, Franck P.

AU - Lucas, Robert J.

AU - Allen, Annette E.

PY - 2019/5/9

Y1 - 2019/5/9

N2 - Under typical daytime light levels, the human pupillary light response (PLR) is driven by the activity of the L, M, and S cones, and melanopsin expressed in the so-called intrinsically photosensitive retinal ganglion cells (ipRGCs). However, the importance of each of these photoreceptive mechanisms in defining pupil size under real-world viewing conditions remains to be established. To address this question, we embedded photoreceptor-specific modulations in a movie displayed using a novel projector-based five-primary spatial stimulation system, which allowed for the precise control of photoreceptor activations in time and space. We measured the pupillary light response in eleven observers, who viewed short cartoon movies which contained hidden low-frequency (0.25 Hz) silent-substitution modulations of the L, M and S cones (no stimulation of melanopsin), melanopsin (no stimulation of L, M and S cones), both L, M, and S cones and melanopsin or no modulation at all. We find that all photoreceptors active at photopic light levels regulate pupil size under this condition. Our data imply that embedding modulations in photoreceptor contrast could provide a method to manipulate key adaptive aspects of the human visual system in everyday, real-world activities such as watching a movie.

AB - Under typical daytime light levels, the human pupillary light response (PLR) is driven by the activity of the L, M, and S cones, and melanopsin expressed in the so-called intrinsically photosensitive retinal ganglion cells (ipRGCs). However, the importance of each of these photoreceptive mechanisms in defining pupil size under real-world viewing conditions remains to be established. To address this question, we embedded photoreceptor-specific modulations in a movie displayed using a novel projector-based five-primary spatial stimulation system, which allowed for the precise control of photoreceptor activations in time and space. We measured the pupillary light response in eleven observers, who viewed short cartoon movies which contained hidden low-frequency (0.25 Hz) silent-substitution modulations of the L, M and S cones (no stimulation of melanopsin), melanopsin (no stimulation of L, M and S cones), both L, M, and S cones and melanopsin or no modulation at all. We find that all photoreceptors active at photopic light levels regulate pupil size under this condition. Our data imply that embedding modulations in photoreceptor contrast could provide a method to manipulate key adaptive aspects of the human visual system in everyday, real-world activities such as watching a movie.

U2 - 10.1371/journal.pone.0216307

DO - 10.1371/journal.pone.0216307

M3 - Article

C2 - 31071113

AN - SCOPUS:85065637689

VL - 14

JO - PL o S One

JF - PL o S One

SN - 1932-6203

IS - 5

M1 - e0216307

ER -