Photoredox Imino-Functionalizations of Olefins

Research output: Contribution to journalArticle

  • Authors:
  • Jacob Davies
  • Nadeem S Sheikh
  • Daniele Leonori

Abstract

Herein, we show that poly-functionalized nitrogen heterocycles can be easily prepared by a visible-light-mediated radical cascade process. This divergent strategy features the oxidative generation of iminyl radicals and their cascade cyclization–radical trapping, which allows the effective construction of highly functionalized heterocycles. The reactions proceed efficiently at room temperature, utilize an organic photocatalyst, use simple and readily available materials and generate, in a single step, valuable building blocks that would be difficult to prepare by other methods.

Bibliographical metadata

Original languageEnglish
Pages (from-to)13361-13365
Number of pages5
JournalAngewandte Chemie - International Edition
Volume56
Issue number43
Early online date22 Sep 2017
DOIs
Publication statusPublished - 11 Oct 2017