Photoinduced decarboxylative azidation of cyclic amino acids

Research output: Contribution to journalArticle

  • Authors:
  • David C. Marcote
  • Rosie Street-Jeakings
  • Elizabeth Dauncey
  • James J. Douglas
  • Alessandro Ruffoni
  • And 1 others
  • External authors:
  • Daniele Leonori

Abstract

The direct decarboxylative azidation of cyclic α-amino acids has been achieved via visible light-mediated organo-photoredox catalysis. This synthetic strategy allows the simple preparation of azide-contaning building blocks and has been used in the selective modification of N-terminal proline residues of two di-peptides.

Bibliographical metadata

Original languageEnglish
Pages (from-to)1839-1842
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume17
Issue number7
Early online date26 Dec 2018
DOIs
Publication statusPublished - 1 Jan 2019