Phosphate enrichment of dialysate for use in standard and extended haemodialysisCitation formats

  • External authors:
  • Leonard M Ebah
  • Mehvosh Akhtar
  • Ian Wilde
  • Graeme Hookway
  • Mark Vincent
  • Christopher Reeves
  • John Denton
  • John Woods

Standard

Phosphate enrichment of dialysate for use in standard and extended haemodialysis. / Ebah, Leonard M; Akhtar, Mehvosh; Wilde, Ian; Hookway, Graeme; Vincent, Mark; Reeves, Christopher; Denton, John; Woods, John; Mitra, Sandip.

In: Blood Purification, Vol. 34, No. 1, 2012, p. 28-33.

Research output: Contribution to journalArticlepeer-review

Harvard

Ebah, LM, Akhtar, M, Wilde, I, Hookway, G, Vincent, M, Reeves, C, Denton, J, Woods, J & Mitra, S 2012, 'Phosphate enrichment of dialysate for use in standard and extended haemodialysis', Blood Purification, vol. 34, no. 1, pp. 28-33. https://doi.org/10.1159/000339818, https://doi.org/10.1159/000339818

APA

Ebah, L. M., Akhtar, M., Wilde, I., Hookway, G., Vincent, M., Reeves, C., Denton, J., Woods, J., & Mitra, S. (2012). Phosphate enrichment of dialysate for use in standard and extended haemodialysis. Blood Purification, 34(1), 28-33. https://doi.org/10.1159/000339818, https://doi.org/10.1159/000339818

Vancouver

Ebah LM, Akhtar M, Wilde I, Hookway G, Vincent M, Reeves C et al. Phosphate enrichment of dialysate for use in standard and extended haemodialysis. Blood Purification. 2012;34(1):28-33. https://doi.org/10.1159/000339818, https://doi.org/10.1159/000339818

Author

Ebah, Leonard M ; Akhtar, Mehvosh ; Wilde, Ian ; Hookway, Graeme ; Vincent, Mark ; Reeves, Christopher ; Denton, John ; Woods, John ; Mitra, Sandip. / Phosphate enrichment of dialysate for use in standard and extended haemodialysis. In: Blood Purification. 2012 ; Vol. 34, No. 1. pp. 28-33.

Bibtex

@article{1085c38e7f5d482abd3fe0165648cfc6,
title = "Phosphate enrichment of dialysate for use in standard and extended haemodialysis",
abstract = "BACKGROUND/AIMS: Intensive haemodialysis (HD) sometimes causes hypophosphataemia, but phosphate-containing dialysate is not readily available. We examined the effectiveness of extemporaneously producing a phosphate-rich dialysate for use in HD.METHODS: Incremental volumes of Fleet{\textregistered} were added to acid concentrate and predicted to deliver dialysate phosphate concentrations of 0.19-1.1 mmol/l, following mixture with ultrapure water and base concentrate by the HD machine.RESULTS: The achieved concentrations were close to predicted values (p = 0.77) and remained stable throughout an 8-hour 'treatment' time (p = 0.99). The dialysate phosphate concentration had a linear relationship with the Fleet{\textregistered} volume added, defined by the regression equation y = 172.79 x - 1.47 (R(2) = 0.99, r = 0.99, p = 0.003). The dialysate pH, calcium, magnesium and bicarbonate concentrations did not change over the study period (p = 0.28-0.99). Microscopic analysis under polarised light showed no evidence of crystal formation.CONCLUSION: The study validates a simple, reliable and cost-effective protocol for phosphate supplementation in conventional and extended HD.",
keywords = "Calcium, Dialysate, Haemodialysis, Hypophosphataemia, Phosphate",
author = "Ebah, {Leonard M} and Mehvosh Akhtar and Ian Wilde and Graeme Hookway and Mark Vincent and Christopher Reeves and John Denton and John Woods and Sandip Mitra",
note = "Copyright {\textcopyright} 2012 S. Karger AG, Basel.",
year = "2012",
doi = "10.1159/000339818",
language = "English",
volume = "34",
pages = "28--33",
journal = "Blood Purification",
issn = "0253-5068",
publisher = "S. Karger AG",
number = "1",

}

RIS

TY - JOUR

T1 - Phosphate enrichment of dialysate for use in standard and extended haemodialysis

AU - Ebah, Leonard M

AU - Akhtar, Mehvosh

AU - Wilde, Ian

AU - Hookway, Graeme

AU - Vincent, Mark

AU - Reeves, Christopher

AU - Denton, John

AU - Woods, John

AU - Mitra, Sandip

N1 - Copyright © 2012 S. Karger AG, Basel.

PY - 2012

Y1 - 2012

N2 - BACKGROUND/AIMS: Intensive haemodialysis (HD) sometimes causes hypophosphataemia, but phosphate-containing dialysate is not readily available. We examined the effectiveness of extemporaneously producing a phosphate-rich dialysate for use in HD.METHODS: Incremental volumes of Fleet® were added to acid concentrate and predicted to deliver dialysate phosphate concentrations of 0.19-1.1 mmol/l, following mixture with ultrapure water and base concentrate by the HD machine.RESULTS: The achieved concentrations were close to predicted values (p = 0.77) and remained stable throughout an 8-hour 'treatment' time (p = 0.99). The dialysate phosphate concentration had a linear relationship with the Fleet® volume added, defined by the regression equation y = 172.79 x - 1.47 (R(2) = 0.99, r = 0.99, p = 0.003). The dialysate pH, calcium, magnesium and bicarbonate concentrations did not change over the study period (p = 0.28-0.99). Microscopic analysis under polarised light showed no evidence of crystal formation.CONCLUSION: The study validates a simple, reliable and cost-effective protocol for phosphate supplementation in conventional and extended HD.

AB - BACKGROUND/AIMS: Intensive haemodialysis (HD) sometimes causes hypophosphataemia, but phosphate-containing dialysate is not readily available. We examined the effectiveness of extemporaneously producing a phosphate-rich dialysate for use in HD.METHODS: Incremental volumes of Fleet® were added to acid concentrate and predicted to deliver dialysate phosphate concentrations of 0.19-1.1 mmol/l, following mixture with ultrapure water and base concentrate by the HD machine.RESULTS: The achieved concentrations were close to predicted values (p = 0.77) and remained stable throughout an 8-hour 'treatment' time (p = 0.99). The dialysate phosphate concentration had a linear relationship with the Fleet® volume added, defined by the regression equation y = 172.79 x - 1.47 (R(2) = 0.99, r = 0.99, p = 0.003). The dialysate pH, calcium, magnesium and bicarbonate concentrations did not change over the study period (p = 0.28-0.99). Microscopic analysis under polarised light showed no evidence of crystal formation.CONCLUSION: The study validates a simple, reliable and cost-effective protocol for phosphate supplementation in conventional and extended HD.

KW - Calcium

KW - Dialysate

KW - Haemodialysis

KW - Hypophosphataemia

KW - Phosphate

U2 - 10.1159/000339818

DO - 10.1159/000339818

M3 - Article

C2 - 22889988

VL - 34

SP - 28

EP - 33

JO - Blood Purification

JF - Blood Purification

SN - 0253-5068

IS - 1

ER -