Occupation exposures and sperm morphology: A case-referent analysis of a multi-centre study

Research output: Contribution to journalArticle

  • External authors:
  • Nicola Cherry
  • Roseanne McNamee
  • Harry Moore
  • Helen Baillie
  • Julie Ann Clyma
  • Martin Dippnall
  • Allan A. Pacey

Abstract

Objective: We examined occupational exposures and sperm morphology to establish whether exposures implicated differed from those affecting motile sperm concentration. Methods: Computer aided sperm morphometric assessment was undertaken on morphology slides obtained as part of a multi-centre study in 1999-2002 of occupational factors in male infertility. Men attending 14 fertility clinics across the UK were recruited and gave a semen sample. Before results of the semen analysis were known, the men completed detailed questionnaires about their employment and lifestyle. Occupational exposures were assessed by occupational hygienists. Data were analysed using an unmatched case-referent design, allowing for clustering and for confounders. Three case definitions were used: poor morphology (normal morphology

Bibliographical metadata

Original languageEnglish
Pages (from-to)598-604
Number of pages6
JournalOccupational and Environmental Medicine
Volume71
Issue number9
DOIs
Publication statusPublished - 2014