Obesity-related hypertension: Epidemiology, pathophysiology, treatments, and the contribution of perivascular adipose tissue

Research output: Contribution to journalArticle


The advent of the obesity epidemic has highlighted the need to re-assess more closely the pathophysiology of obesity-related hypertension with the aim of identifying new therapies. In this article, we review the role of the renin-angiotensin-aldosterone system, sympathetic nervous system, and inflammation in relation to the pathophysiology of this condition. We also discuss the potential role of the perivascular adipose tissue in the context of obesity-related hypertension. © 2012 Informa UK, Ltd.

Bibliographical metadata

Original languageEnglish
Pages (from-to)S74-S84
JournalAnnals of Medicine
Issue number1
Publication statusPublished - Jun 2012