Low-frequency local field potentials and spikes in primary visual cortex convey independent visual information

Research output: Contribution to journalArticlepeer-review

  • Authors:
  • Andrei Belitski
  • Arthur Gretton
  • Cesare Magri
  • Yusuke Murayama
  • Marcelo A. Montemurro
  • And 2 others
  • External authors:
  • Nikos K. Logothetis
  • Stefano Panzeri

Abstract

Local field potentials (LFPs) reflect subthreshold integrative processes that complement spike train measures. However, little is yet known about the differences between how LFPs and spikes encode rich naturalistic sensory stimuli. We addressed this question by recording LFPs and spikes from the primary visual cortex of anesthetized macaques while presenting a color movie. We then determined how the power of LFPs and spikes at different frequencies represents the visual features in the movie. We found that the most informative LFP frequency ranges were 1-8 and 60-100 Hz. LFPs in the range of 12-40 Hz carried little information about the stimulus, and may primarily reflect neuromodulatory inputs. Spike power was informative only at frequencies 40 Hz and with spikes, suggesting that low-frequency LFPs reflect neural processes that in natural conditions are fully decoupled from those giving rise to spikes and to high-gamma LFPs. Copyright © 2008 Society for Neuroscience.

Bibliographical metadata

Original languageEnglish
Pages (from-to)5696-5709
Number of pages13
JournalJournal of Neuroscience
Volume28
Issue number22
DOIs
Publication statusPublished - 28 May 2008