Is chest pain after sumatriptan oesophageal in origin?

Research output: Contribution to journalArticle

  • Authors:
  • Lesley A. Houghton
  • Joanne M. Foster
  • P. J. Whorwell
  • Julie Morris
  • Patricia Fowler


3-5% of patients taking the 5HT(1D) agonist sumatriptan for migraine have chest discomfort, suggesting a cardiac origin. We have investigated an alternative explanation of an eosophageal administration of a supratherapeutic dose of sumatriptan (16 mg) or placebo in a randomised, double-blind crossover study. Sumatriptan did not alter the electrocardiogram but increased the amplitude (p

Bibliographical metadata

Original languageEnglish
Pages (from-to)985-986
Number of pages1
JournalThe Lancet
Issue number8928
Publication statusPublished - 1994