Introduction to metabolomics and its applications in ophthalmology

Research output: Contribution to journalArticle

  • Authors:
  • S Z Tan
  • P Begley
  • G Mullard
  • K A Hollywood
  • P N Bishop

Abstract

Metabolomics is the study of endogenous and exogenous metabolites in biological systems, which aims to provide comparative semi-quantitative information about all metabolites in the system. Metabolomics is an emerging and potentially powerful tool in ophthalmology research. It is therefore important for health professionals and researchers involved in the speciality to understand the basic principles of metabolomics experiments. This article provides an overview of the experimental workflow and examples of its use in ophthalmology research from the study of disease metabolism and pathogenesis to identification of biomarkers.

Bibliographical metadata

Original languageEnglish
Pages (from-to)773-783
Number of pages11
JournalEye (London, England)
Volume30
Issue number6
Early online date18 Mar 2016
DOIs
Publication statusPublished - Jun 2016