Innate immune cell suppression and the link with secondary lung bacterial pneumoniaCitation formats

  • External authors:
  • Joshua Casulli
  • Christine Chew
  • Emma Connolly
  • Oliver Brand
  • Rizwana Rahman
  • Christopher Jagger

Standard

Innate immune cell suppression and the link with secondary lung bacterial pneumonia. / Morgan, David; Casulli, Joshua; Chew, Christine; Connolly, Emma; Lui, Sylvia; Brand, Oliver; Rahman, Rizwana; Jagger, Christopher; Hussell, Tracy.

In: Frontiers in Immunology, 30.11.2018.

Research output: Contribution to journalArticle

Harvard

Morgan, D, Casulli, J, Chew, C, Connolly, E, Lui, S, Brand, O, Rahman, R, Jagger, C & Hussell, T 2018, 'Innate immune cell suppression and the link with secondary lung bacterial pneumonia', Frontiers in Immunology. https://doi.org/10.3389/fimmu.2018.02943

APA

Vancouver

Author

Morgan, David ; Casulli, Joshua ; Chew, Christine ; Connolly, Emma ; Lui, Sylvia ; Brand, Oliver ; Rahman, Rizwana ; Jagger, Christopher ; Hussell, Tracy. / Innate immune cell suppression and the link with secondary lung bacterial pneumonia. In: Frontiers in Immunology. 2018.

Bibtex

@article{26b9b79496e94d30b45185a099874eaf,
title = "Innate immune cell suppression and the link with secondary lung bacterial pneumonia",
abstract = "Secondary infections arise as a consequence of previous or concurrent conditions and occur in the community or in the hospital setting. The events allowing secondary infections to gain a foothold have been studied for many years and include poor nutrition, anxiety, mental health issues, underlying chronic diseases, resolution of acute inflammation, primary immune deficiencies and immune suppression by infection or medication. Children, the elderly and the ill are particularly susceptible. This review is concerned with secondary bacterial infections of the lung that occur following viral infection. Using influenza virus infection as an example, with comparisons to rhinovirus and respiratory syncytial virus infection, we will update and review defective bacterial innate immunity and also highlight areas for potential new investigation. It is currently estimated that one in sixteen National Health Service (NHS) hospital patients develop an infection, the most common being pneumonia, lower respiratory tract infections, urinary tract infections and infection of surgical sites. The continued drive to understand the mechanisms of why secondary infections arise is therefore of key importance.",
author = "David Morgan and Joshua Casulli and Christine Chew and Emma Connolly and Sylvia Lui and Oliver Brand and Rizwana Rahman and Christopher Jagger and Tracy Hussell",
year = "2018",
month = "11",
day = "30",
doi = "10.3389/fimmu.2018.02943",
language = "English",
journal = "Frontiers in Immunology",
issn = "1664-3224",
publisher = "Frontiers Media S. A.",

}

RIS

TY - JOUR

T1 - Innate immune cell suppression and the link with secondary lung bacterial pneumonia

AU - Morgan, David

AU - Casulli, Joshua

AU - Chew, Christine

AU - Connolly, Emma

AU - Lui, Sylvia

AU - Brand, Oliver

AU - Rahman, Rizwana

AU - Jagger, Christopher

AU - Hussell, Tracy

PY - 2018/11/30

Y1 - 2018/11/30

N2 - Secondary infections arise as a consequence of previous or concurrent conditions and occur in the community or in the hospital setting. The events allowing secondary infections to gain a foothold have been studied for many years and include poor nutrition, anxiety, mental health issues, underlying chronic diseases, resolution of acute inflammation, primary immune deficiencies and immune suppression by infection or medication. Children, the elderly and the ill are particularly susceptible. This review is concerned with secondary bacterial infections of the lung that occur following viral infection. Using influenza virus infection as an example, with comparisons to rhinovirus and respiratory syncytial virus infection, we will update and review defective bacterial innate immunity and also highlight areas for potential new investigation. It is currently estimated that one in sixteen National Health Service (NHS) hospital patients develop an infection, the most common being pneumonia, lower respiratory tract infections, urinary tract infections and infection of surgical sites. The continued drive to understand the mechanisms of why secondary infections arise is therefore of key importance.

AB - Secondary infections arise as a consequence of previous or concurrent conditions and occur in the community or in the hospital setting. The events allowing secondary infections to gain a foothold have been studied for many years and include poor nutrition, anxiety, mental health issues, underlying chronic diseases, resolution of acute inflammation, primary immune deficiencies and immune suppression by infection or medication. Children, the elderly and the ill are particularly susceptible. This review is concerned with secondary bacterial infections of the lung that occur following viral infection. Using influenza virus infection as an example, with comparisons to rhinovirus and respiratory syncytial virus infection, we will update and review defective bacterial innate immunity and also highlight areas for potential new investigation. It is currently estimated that one in sixteen National Health Service (NHS) hospital patients develop an infection, the most common being pneumonia, lower respiratory tract infections, urinary tract infections and infection of surgical sites. The continued drive to understand the mechanisms of why secondary infections arise is therefore of key importance.

U2 - 10.3389/fimmu.2018.02943

DO - 10.3389/fimmu.2018.02943

M3 - Article

JO - Frontiers in Immunology

JF - Frontiers in Immunology

SN - 1664-3224

ER -