Impact of Using Conventional Inlet/Outlet Boundary Conditions on Haemodynamic Metrics in a Subject-Specific Rabbit Aorta

Research output: Contribution to journalArticle

Abstract

Computational fluid dynamics is a tool capable of accurately measuring metrics currently used to predict the behaviour of cardiovascular diseases. This study quantifies the impact various commonly used inlet and outlet boundary conditions have on various shear rate–based haemodynamic metrics currently used for predicting the localisation of cardiovascular diseases. Simulations are conducted on an accurately represented rabbit aorta configuration and comparison has been made against available in vivo data. The boundary conditions studied include two different inlet profiles, three outlet boundary conditions, and steady-state versus pulsatile flow cases. Large variations were found in the results, particularly when using different outlet boundary conditions, and the discrepancies were evaluated both quantitatively and qualitatively. The results clearly highlight the importance of the type of boundary condition used when simulating complex cardiovascular models. By restricting the attention to the flow withi...

Bibliographical metadata

Original languageEnglish
Pages (from-to)103-113
Number of pages11
JournalProceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
Volume232
Issue number2
Early online date25 Mar 2017
DOIs
Publication statusPublished - 1 Feb 2018