Impact of daily anatomical changes on EPID-based in vivo dosimetry of VMAT treatments of head-and-neck cancer.Citation formats

  • External authors:
  • Roel A Rozendaal
  • Ben J Mijnheer
  • Olga Hamming-Vrieze
  • Anton Mans
  • Marcel van Herk

Standard

Impact of daily anatomical changes on EPID-based in vivo dosimetry of VMAT treatments of head-and-neck cancer. / Van Herk, Marcel; Rozendaal, Roel A; Mijnheer, Ben J; Hamming-Vrieze, Olga; Mans, Anton; van Herk, Marcel.

In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 30.06.2015.

Research output: Contribution to journalArticle

Harvard

Van Herk, M, Rozendaal, RA, Mijnheer, BJ, Hamming-Vrieze, O, Mans, A & van Herk, M 2015, 'Impact of daily anatomical changes on EPID-based in vivo dosimetry of VMAT treatments of head-and-neck cancer.', Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. https://doi.org/10.1016/j.radonc.2015.05.020

APA

Van Herk, M., Rozendaal, R. A., Mijnheer, B. J., Hamming-Vrieze, O., Mans, A., & van Herk, M. (2015). Impact of daily anatomical changes on EPID-based in vivo dosimetry of VMAT treatments of head-and-neck cancer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. https://doi.org/10.1016/j.radonc.2015.05.020

Vancouver

Van Herk M, Rozendaal RA, Mijnheer BJ, Hamming-Vrieze O, Mans A, van Herk M. Impact of daily anatomical changes on EPID-based in vivo dosimetry of VMAT treatments of head-and-neck cancer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2015 Jun 30. https://doi.org/10.1016/j.radonc.2015.05.020

Author

Van Herk, Marcel ; Rozendaal, Roel A ; Mijnheer, Ben J ; Hamming-Vrieze, Olga ; Mans, Anton ; van Herk, Marcel. / Impact of daily anatomical changes on EPID-based in vivo dosimetry of VMAT treatments of head-and-neck cancer. In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 2015.

Bibtex

@article{cfebd6711ab4483f91a1e647c7b8c73e,
title = "Impact of daily anatomical changes on EPID-based in vivo dosimetry of VMAT treatments of head-and-neck cancer.",
abstract = "BACKGROUND AND PURPOSE: Target dose verification for VMAT treatments of head-and-neck (H&N) cancer using 3D in vivo EPID dosimetry is expected to be affected by daily anatomical changes. By including these anatomical changes through cone-beam CT (CBCT) information, the magnitude of this effect is investigated. MATERIALS AND METHODS: For 20 VMAT-treated H&N cancer patients, all plan-CTs (pCTs), 633 CBCTs and 1266 EPID movies were used to compare four dose distributions per fraction: treatment planning system (TPS) calculated dose and EPID reconstructed in vivo dose, both determined using the pCT and using the CBCT. D2, D50 and D98 of the planning target volume (PTV) were determined per dose distribution. RESULTS: When including daily anatomical information, D2, D50 and D98 of the PTV change on average by 0.0±0.4{\%} according to TPS calculations; the standard deviation of the difference between EPID and TPS target dose changes from 2.5{\%} (pCT) to 2.1{\%} (CBCT). Small time trends are seen for both TPS and EPID dose distributions when using the pCT, which disappear when including CBCT information. CONCLUSIONS: Daily anatomical changes hardly influence the target dose distribution for H&N VMAT treatments according to TPS recalculations. Including CBCT information in EPID dose reconstructions slightly improves the agreement with TPS calculations.",
keywords = "Anatomical changes, EPID dosimetry, In vivo QA",
author = "{Van Herk}, Marcel and Rozendaal, {Roel A} and Mijnheer, {Ben J} and Olga Hamming-Vrieze and Anton Mans and {van Herk}, Marcel",
year = "2015",
month = "6",
day = "30",
doi = "10.1016/j.radonc.2015.05.020",
language = "English",
journal = "Radiotherapy & Oncology",
issn = "0167-8140",
publisher = "Elsevier BV",

}

RIS

TY - JOUR

T1 - Impact of daily anatomical changes on EPID-based in vivo dosimetry of VMAT treatments of head-and-neck cancer.

AU - Van Herk, Marcel

AU - Rozendaal, Roel A

AU - Mijnheer, Ben J

AU - Hamming-Vrieze, Olga

AU - Mans, Anton

AU - van Herk, Marcel

PY - 2015/6/30

Y1 - 2015/6/30

N2 - BACKGROUND AND PURPOSE: Target dose verification for VMAT treatments of head-and-neck (H&N) cancer using 3D in vivo EPID dosimetry is expected to be affected by daily anatomical changes. By including these anatomical changes through cone-beam CT (CBCT) information, the magnitude of this effect is investigated. MATERIALS AND METHODS: For 20 VMAT-treated H&N cancer patients, all plan-CTs (pCTs), 633 CBCTs and 1266 EPID movies were used to compare four dose distributions per fraction: treatment planning system (TPS) calculated dose and EPID reconstructed in vivo dose, both determined using the pCT and using the CBCT. D2, D50 and D98 of the planning target volume (PTV) were determined per dose distribution. RESULTS: When including daily anatomical information, D2, D50 and D98 of the PTV change on average by 0.0±0.4% according to TPS calculations; the standard deviation of the difference between EPID and TPS target dose changes from 2.5% (pCT) to 2.1% (CBCT). Small time trends are seen for both TPS and EPID dose distributions when using the pCT, which disappear when including CBCT information. CONCLUSIONS: Daily anatomical changes hardly influence the target dose distribution for H&N VMAT treatments according to TPS recalculations. Including CBCT information in EPID dose reconstructions slightly improves the agreement with TPS calculations.

AB - BACKGROUND AND PURPOSE: Target dose verification for VMAT treatments of head-and-neck (H&N) cancer using 3D in vivo EPID dosimetry is expected to be affected by daily anatomical changes. By including these anatomical changes through cone-beam CT (CBCT) information, the magnitude of this effect is investigated. MATERIALS AND METHODS: For 20 VMAT-treated H&N cancer patients, all plan-CTs (pCTs), 633 CBCTs and 1266 EPID movies were used to compare four dose distributions per fraction: treatment planning system (TPS) calculated dose and EPID reconstructed in vivo dose, both determined using the pCT and using the CBCT. D2, D50 and D98 of the planning target volume (PTV) were determined per dose distribution. RESULTS: When including daily anatomical information, D2, D50 and D98 of the PTV change on average by 0.0±0.4% according to TPS calculations; the standard deviation of the difference between EPID and TPS target dose changes from 2.5% (pCT) to 2.1% (CBCT). Small time trends are seen for both TPS and EPID dose distributions when using the pCT, which disappear when including CBCT information. CONCLUSIONS: Daily anatomical changes hardly influence the target dose distribution for H&N VMAT treatments according to TPS recalculations. Including CBCT information in EPID dose reconstructions slightly improves the agreement with TPS calculations.

KW - Anatomical changes

KW - EPID dosimetry

KW - In vivo QA

U2 - 10.1016/j.radonc.2015.05.020

DO - 10.1016/j.radonc.2015.05.020

M3 - Article

JO - Radiotherapy & Oncology

JF - Radiotherapy & Oncology

SN - 0167-8140

ER -