Heavily fluorinated carbohydrates as enzyme substrates: Oxidation of tetrafluorinated galactose by galactose oxidase

Research output: Contribution to journalArticle

  • External authors:
  • Avgousta Ioannou
  • Elena Cini
  • Roxana S. Timofte
  • Bruno Linclau


Galactose oxidase (GOase) was shown to oxidise several C2/C3 fluorinated galactose analogues. Interestingly, the enzyme was able to distinguish between the 2,3-tetrafluorinated galactose and its epimeric glucose analogue, and this represents the first reported biotransformation of a heavily fluorinated sugar. © 2011 The Royal Society of Chemistry.

Bibliographical metadata

Original languageEnglish
Pages (from-to)11228-11230
Number of pages2
JournalChemical Communications
Issue number40
Publication statusPublished - 28 Oct 2011