HDL antioxidant function is impaired and adipose tissue inflammation is pronounced in obese patients with increasing severity of sleep apnea

Research output: Contribution to conferenceAbstract

  • External authors:
  • R Yadav
  • M France
  • Reza Aghamohammadzadeh
  • Y Liu
  • S Hama
  • S Kwok
  • J Schofield
  • Rayaz Malik
  • Paul Durrington
  • Handrean Soran


Objectives: Obstructive sleep apnea (OSA) is a common disorder in morbidly obese patients and is associated with the development of cardiovascular disease. Tumor necrosis factor α (TNFα), a mediator of vascular inflammation and paraoxonase 1 (PON1), an antioxidant enzyme associated with HDL have opposing effects, but have not been studied systematically in OSA.

Bibliographical metadata

Original languageEnglish
Publication statusPublished - Aug 2014
Event82nd EAS Congress - Madrid
Event duration: 31 May 20143 Jun 2014


Conference82nd EAS Congress