Graphene for multi-functional synthetic biology: The last 'zeitgeist' in nanomedicine

Research output: Contribution to journalArticle

Abstract

The high versatility of graphene has attracted significant attention in many areas of scientific research from electronics to physics and mechanics. One of the most intriguing utilisation of graphene remains however in nanomedicine and synthetic biology. In particular, the last decade has witnessed an exponential growth in the generation of novel candidate therapeutics of multiple biological activities based on graphene constructs with small molecules, such as anti-cancer drugs. In this Digest, we summarise the different synthetic strategies and routes available to fabricate these promising graphene conjugates and the opportunities for the design of multi-functional tools for synthetic biology that they offer. © 2014 Elsevier Ltd. All rights reserved.

Bibliographical metadata

Original languageEnglish
Pages (from-to)1638-1649
Number of pages11
JournalBioorganic and Medicinal Chemistry Letters
Volume24
Issue number7
DOIs
Publication statusPublished - 1 Apr 2014