Genetics and genomics of radiotherapy toxicity: Towards predictionCitation formats

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Genetics and genomics of radiotherapy toxicity: Towards prediction. / West, Catharine M.; Barnett, Gillian C.

In: Genome Medicine, Vol. 3, No. 8, 52, 23.08.2011.

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West, Catharine M. ; Barnett, Gillian C. / Genetics and genomics of radiotherapy toxicity: Towards prediction. In: Genome Medicine. 2011 ; Vol. 3, No. 8.

Bibtex

@article{d25e69bb8a8e4cf5a8f9c3776b16e481,
title = "Genetics and genomics of radiotherapy toxicity: Towards prediction",
abstract = "Radiotherapy is involved in many curative treatments of cancer; millions of survivors live with the consequences of treatment, and toxicity in a minority limits the radiation doses that can be safely prescribed to the majority. Radiogenomics is the whole genome application of radiogenetics, which studies the influence of genetic variation on radiation response. Work in the area focuses on uncovering the underlying genetic causes of individual variation in sensitivity to radiation, which is important for effective, safe treatment. In this review, we highlight recent advances in radiotherapy and discuss results from four genome-wide studies of radiotoxicity. {\textcopyright} 2011 BioMed Central Ltd.",
keywords = "Genome-wide association study, Radiation, Radiothe, Rapyradiogenomics, Single nucleotide polymorphism",
author = "West, {Catharine M.} and Barnett, {Gillian C.}",
year = "2011",
month = aug,
day = "23",
doi = "10.1186/gm268",
language = "English",
volume = "3",
journal = "Genome Medicine",
issn = "1756-994X",
publisher = "BioMed Central Ltd",
number = "8",

}

RIS

TY - JOUR

T1 - Genetics and genomics of radiotherapy toxicity: Towards prediction

AU - West, Catharine M.

AU - Barnett, Gillian C.

PY - 2011/8/23

Y1 - 2011/8/23

N2 - Radiotherapy is involved in many curative treatments of cancer; millions of survivors live with the consequences of treatment, and toxicity in a minority limits the radiation doses that can be safely prescribed to the majority. Radiogenomics is the whole genome application of radiogenetics, which studies the influence of genetic variation on radiation response. Work in the area focuses on uncovering the underlying genetic causes of individual variation in sensitivity to radiation, which is important for effective, safe treatment. In this review, we highlight recent advances in radiotherapy and discuss results from four genome-wide studies of radiotoxicity. © 2011 BioMed Central Ltd.

AB - Radiotherapy is involved in many curative treatments of cancer; millions of survivors live with the consequences of treatment, and toxicity in a minority limits the radiation doses that can be safely prescribed to the majority. Radiogenomics is the whole genome application of radiogenetics, which studies the influence of genetic variation on radiation response. Work in the area focuses on uncovering the underlying genetic causes of individual variation in sensitivity to radiation, which is important for effective, safe treatment. In this review, we highlight recent advances in radiotherapy and discuss results from four genome-wide studies of radiotoxicity. © 2011 BioMed Central Ltd.

KW - Genome-wide association study

KW - Radiation

KW - Radiothe

KW - Rapyradiogenomics

KW - Single nucleotide polymorphism

U2 - 10.1186/gm268

DO - 10.1186/gm268

M3 - Article

VL - 3

JO - Genome Medicine

JF - Genome Medicine

SN - 1756-994X

IS - 8

M1 - 52

ER -