Functional magnetic resonance imaging in dermatologyCitation formats
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Functional magnetic resonance imaging in dermatology : The skin, the brain and the invisible. / Mueller, Simon M; Hogg, Samuel; Mueller, Jannis; McKie, Shane; Itin, Peter; Reinhardt, Julia; Griffiths, Christopher E M; Kleyn, C Elise.
In: Experimental Dermatology, 2017.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Functional magnetic resonance imaging in dermatology
T2 - The skin, the brain and the invisible
AU - Mueller, Simon M
AU - Hogg, Samuel
AU - Mueller, Jannis
AU - McKie, Shane
AU - Itin, Peter
AU - Reinhardt, Julia
AU - Griffiths, Christopher E M
AU - Kleyn, C Elise
N1 - This article is protected by copyright. All rights reserved.
PY - 2017
Y1 - 2017
N2 - The skin and brain have a close bi-directional anatomical and functional connection. Historically, the skin-brain axis and the brain-skin axis have been well described. However, brain function in this context has only recently been demystified with the introduction of functional neuroimaging in dermatology. Functional neuroimaging, especially functional magnetic resonance imaging (fMRI), allows indirect visualisation of brain function. This review looks back to the beginnings of functional neuroimaging in dermatology, summarises the currently available dermatology-related fMRI-studies and discusses the potential future role of fMRI as a stratifying tool in clinical dermatology and in the development of novel therapies. According to the main body of research made in this field, the focus is placed on experimental itch studies, which described the brain structures involved in itch processing, the regulation of the scratch response, contagious itch and itch suppression. This article is protected by copyright. All rights reserved.
AB - The skin and brain have a close bi-directional anatomical and functional connection. Historically, the skin-brain axis and the brain-skin axis have been well described. However, brain function in this context has only recently been demystified with the introduction of functional neuroimaging in dermatology. Functional neuroimaging, especially functional magnetic resonance imaging (fMRI), allows indirect visualisation of brain function. This review looks back to the beginnings of functional neuroimaging in dermatology, summarises the currently available dermatology-related fMRI-studies and discusses the potential future role of fMRI as a stratifying tool in clinical dermatology and in the development of novel therapies. According to the main body of research made in this field, the focus is placed on experimental itch studies, which described the brain structures involved in itch processing, the regulation of the scratch response, contagious itch and itch suppression. This article is protected by copyright. All rights reserved.
U2 - 10.1111/exd.13305
DO - 10.1111/exd.13305
M3 - Article
C2 - 28109199
JO - Experimental Dermatology
JF - Experimental Dermatology
SN - 1600-0625
ER -