FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladder.Citation formats

  • External authors:
  • Caryn Hughes
  • Junaid Iqbal-Wahid
  • Jonathan H Shanks
  • Amanda Eustace
  • Helen Denley
  • Peter J Hoskin
  • Noel W Clarke

Standard

FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladder. / Hughes, Caryn; Iqbal-Wahid, Junaid; Brown, Michael; Shanks, Jonathan H; Eustace, Amanda; Denley, Helen; Hoskin, Peter J; West, Catharine; Clarke, Noel W; Gardner, Peter.

In: Journal of biophotonics, Vol. 6, No. 1, 01.2013, p. 73-87.

Research output: Contribution to journalArticlepeer-review

Harvard

Hughes, C, Iqbal-Wahid, J, Brown, M, Shanks, JH, Eustace, A, Denley, H, Hoskin, PJ, West, C, Clarke, NW & Gardner, P 2013, 'FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladder.', Journal of biophotonics, vol. 6, no. 1, pp. 73-87. https://doi.org/10.1002/jbio.201200126

APA

Hughes, C., Iqbal-Wahid, J., Brown, M., Shanks, J. H., Eustace, A., Denley, H., Hoskin, P. J., West, C., Clarke, N. W., & Gardner, P. (2013). FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladder. Journal of biophotonics, 6(1), 73-87. https://doi.org/10.1002/jbio.201200126

Vancouver

Hughes C, Iqbal-Wahid J, Brown M, Shanks JH, Eustace A, Denley H et al. FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladder. Journal of biophotonics. 2013 Jan;6(1):73-87. https://doi.org/10.1002/jbio.201200126

Author

Hughes, Caryn ; Iqbal-Wahid, Junaid ; Brown, Michael ; Shanks, Jonathan H ; Eustace, Amanda ; Denley, Helen ; Hoskin, Peter J ; West, Catharine ; Clarke, Noel W ; Gardner, Peter. / FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladder. In: Journal of biophotonics. 2013 ; Vol. 6, No. 1. pp. 73-87.

Bibtex

@article{7e991d1264be4868a91195ca3966173b,
title = "FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladder.",
abstract = "Urothelial carcinomas of the bladder are a heterogeneous group of tumours, although some histological sub-variants are rare and sparsely reported in the literature. Diagnosis of sub-variants from conventional urothelial carcinoma can be challenging, as they may mimic the morphology of other malignancies or benign tumours and therefore their distinction is important. For the first time, the spectral pathology of some of these sub-variants has been documented by infrared microspectroscopy and an attempt made to profile their biochemistry. It is important not only to identify and separate the cancer-associated epithelial tissue spectra from common tissue features such as stroma or blood, but also to detect the signatures of tumour sub-variants. As shown, their spectroscopic signals can change dramatically as a consequence of differentiation. Example cases are discussed and compared with histological evaluations.",
keywords = "Clear cell, Cluster analysis, FTIR, Infrared microspectroscopy, Lipoid, Principal component analysis, Support vector machines, Transitional cell carcinoma, Urothelial carcinoma",
author = "Caryn Hughes and Junaid Iqbal-Wahid and Michael Brown and Shanks, {Jonathan H} and Amanda Eustace and Helen Denley and Hoskin, {Peter J} and Catharine West and Clarke, {Noel W} and Peter Gardner",
year = "2013",
month = jan,
doi = "10.1002/jbio.201200126",
language = "English",
volume = "6",
pages = "73--87",
journal = "Journal of Biophotonics",
issn = "1864-063X",
publisher = "John Wiley & Sons Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - FTIR microspectroscopy of selected rare diverse sub-variants of carcinoma of the urinary bladder.

AU - Hughes, Caryn

AU - Iqbal-Wahid, Junaid

AU - Brown, Michael

AU - Shanks, Jonathan H

AU - Eustace, Amanda

AU - Denley, Helen

AU - Hoskin, Peter J

AU - West, Catharine

AU - Clarke, Noel W

AU - Gardner, Peter

PY - 2013/1

Y1 - 2013/1

N2 - Urothelial carcinomas of the bladder are a heterogeneous group of tumours, although some histological sub-variants are rare and sparsely reported in the literature. Diagnosis of sub-variants from conventional urothelial carcinoma can be challenging, as they may mimic the morphology of other malignancies or benign tumours and therefore their distinction is important. For the first time, the spectral pathology of some of these sub-variants has been documented by infrared microspectroscopy and an attempt made to profile their biochemistry. It is important not only to identify and separate the cancer-associated epithelial tissue spectra from common tissue features such as stroma or blood, but also to detect the signatures of tumour sub-variants. As shown, their spectroscopic signals can change dramatically as a consequence of differentiation. Example cases are discussed and compared with histological evaluations.

AB - Urothelial carcinomas of the bladder are a heterogeneous group of tumours, although some histological sub-variants are rare and sparsely reported in the literature. Diagnosis of sub-variants from conventional urothelial carcinoma can be challenging, as they may mimic the morphology of other malignancies or benign tumours and therefore their distinction is important. For the first time, the spectral pathology of some of these sub-variants has been documented by infrared microspectroscopy and an attempt made to profile their biochemistry. It is important not only to identify and separate the cancer-associated epithelial tissue spectra from common tissue features such as stroma or blood, but also to detect the signatures of tumour sub-variants. As shown, their spectroscopic signals can change dramatically as a consequence of differentiation. Example cases are discussed and compared with histological evaluations.

KW - Clear cell

KW - Cluster analysis

KW - FTIR

KW - Infrared microspectroscopy

KW - Lipoid

KW - Principal component analysis

KW - Support vector machines

KW - Transitional cell carcinoma

KW - Urothelial carcinoma

U2 - 10.1002/jbio.201200126

DO - 10.1002/jbio.201200126

M3 - Article

C2 - 23125109

VL - 6

SP - 73

EP - 87

JO - Journal of Biophotonics

JF - Journal of Biophotonics

SN - 1864-063X

IS - 1

ER -