'Fish matters': The relevance of fish skin biology to investigative dermatologyCitation formats

  • External authors:
  • Sebastian Rakers
  • Marina Gebert
  • Sai Uppalapati
  • Wilfried Meyer
  • Paul Maderson
  • Anne F. Sell
  • Charli Kruse

Standard

'Fish matters': The relevance of fish skin biology to investigative dermatology. / Rakers, Sebastian; Gebert, Marina; Uppalapati, Sai; Meyer, Wilfried; Maderson, Paul; Sell, Anne F.; Kruse, Charli; Paus, Ralf.

In: Experimental Dermatology, Vol. 19, No. 4, 04.2010, p. 313-324.

Research output: Contribution to journalArticlepeer-review

Harvard

Rakers, S, Gebert, M, Uppalapati, S, Meyer, W, Maderson, P, Sell, AF, Kruse, C & Paus, R 2010, ''Fish matters': The relevance of fish skin biology to investigative dermatology', Experimental Dermatology, vol. 19, no. 4, pp. 313-324. https://doi.org/10.1111/j.1600-0625.2009.01059.x

APA

Rakers, S., Gebert, M., Uppalapati, S., Meyer, W., Maderson, P., Sell, A. F., Kruse, C., & Paus, R. (2010). 'Fish matters': The relevance of fish skin biology to investigative dermatology. Experimental Dermatology, 19(4), 313-324. https://doi.org/10.1111/j.1600-0625.2009.01059.x

Vancouver

Rakers S, Gebert M, Uppalapati S, Meyer W, Maderson P, Sell AF et al. 'Fish matters': The relevance of fish skin biology to investigative dermatology. Experimental Dermatology. 2010 Apr;19(4):313-324. https://doi.org/10.1111/j.1600-0625.2009.01059.x

Author

Rakers, Sebastian ; Gebert, Marina ; Uppalapati, Sai ; Meyer, Wilfried ; Maderson, Paul ; Sell, Anne F. ; Kruse, Charli ; Paus, Ralf. / 'Fish matters': The relevance of fish skin biology to investigative dermatology. In: Experimental Dermatology. 2010 ; Vol. 19, No. 4. pp. 313-324.

Bibtex

@article{d2800768a6414385bf11908432660e0a,
title = "'Fish matters': The relevance of fish skin biology to investigative dermatology",
abstract = "Fish skin is a multi-purpose tissue that serves numerous vital functions including chemical and physical protection, sensory activity, behavioural purposes or hormone metabolism. Further, it is an important first-line defense system against pathogens, as fish are continuously exposed to multiple microbial challenges in their aquatic habitat. Fish skin excels in highly developed antimicrobial features, many of which have been preserved throughout evolution, and infection defense principles employed by piscine skin are still operative in human skin. This review argues that it is both rewarding and important for investigative dermatologists to revive their interest in fish skin biology, as it provides insights into numerous fundamental issues that are of major relevance to mammalian skin. The basic molecular insights provided by zebrafish in vivo-genomics for genetic, regeneration and melanoma research, the complex antimicrobial defense systems of fish skin and the molecular controls of melanocyte stem cells are just some of the fascinating examples that illustrate the multiple potential uses of fish skin models in investigative dermatology. We synthesize the essentials of fish skin biology and highlight selected aspects that are of particular comparative interest to basic and clinically applied human skin research. {\textcopyright} 2010 John Wiley & Sons A/S.",
keywords = "Antimicrobial defense, Epidermis, Fish skin, Fish stem cells, Mucus",
author = "Sebastian Rakers and Marina Gebert and Sai Uppalapati and Wilfried Meyer and Paul Maderson and Sell, {Anne F.} and Charli Kruse and Ralf Paus",
year = "2010",
month = apr,
doi = "10.1111/j.1600-0625.2009.01059.x",
language = "English",
volume = "19",
pages = "313--324",
journal = "Experimental Dermatology",
issn = "1600-0625",
publisher = "John Wiley & Sons Ltd",
number = "4",

}

RIS

TY - JOUR

T1 - 'Fish matters': The relevance of fish skin biology to investigative dermatology

AU - Rakers, Sebastian

AU - Gebert, Marina

AU - Uppalapati, Sai

AU - Meyer, Wilfried

AU - Maderson, Paul

AU - Sell, Anne F.

AU - Kruse, Charli

AU - Paus, Ralf

PY - 2010/4

Y1 - 2010/4

N2 - Fish skin is a multi-purpose tissue that serves numerous vital functions including chemical and physical protection, sensory activity, behavioural purposes or hormone metabolism. Further, it is an important first-line defense system against pathogens, as fish are continuously exposed to multiple microbial challenges in their aquatic habitat. Fish skin excels in highly developed antimicrobial features, many of which have been preserved throughout evolution, and infection defense principles employed by piscine skin are still operative in human skin. This review argues that it is both rewarding and important for investigative dermatologists to revive their interest in fish skin biology, as it provides insights into numerous fundamental issues that are of major relevance to mammalian skin. The basic molecular insights provided by zebrafish in vivo-genomics for genetic, regeneration and melanoma research, the complex antimicrobial defense systems of fish skin and the molecular controls of melanocyte stem cells are just some of the fascinating examples that illustrate the multiple potential uses of fish skin models in investigative dermatology. We synthesize the essentials of fish skin biology and highlight selected aspects that are of particular comparative interest to basic and clinically applied human skin research. © 2010 John Wiley & Sons A/S.

AB - Fish skin is a multi-purpose tissue that serves numerous vital functions including chemical and physical protection, sensory activity, behavioural purposes or hormone metabolism. Further, it is an important first-line defense system against pathogens, as fish are continuously exposed to multiple microbial challenges in their aquatic habitat. Fish skin excels in highly developed antimicrobial features, many of which have been preserved throughout evolution, and infection defense principles employed by piscine skin are still operative in human skin. This review argues that it is both rewarding and important for investigative dermatologists to revive their interest in fish skin biology, as it provides insights into numerous fundamental issues that are of major relevance to mammalian skin. The basic molecular insights provided by zebrafish in vivo-genomics for genetic, regeneration and melanoma research, the complex antimicrobial defense systems of fish skin and the molecular controls of melanocyte stem cells are just some of the fascinating examples that illustrate the multiple potential uses of fish skin models in investigative dermatology. We synthesize the essentials of fish skin biology and highlight selected aspects that are of particular comparative interest to basic and clinically applied human skin research. © 2010 John Wiley & Sons A/S.

KW - Antimicrobial defense

KW - Epidermis

KW - Fish skin

KW - Fish stem cells

KW - Mucus

U2 - 10.1111/j.1600-0625.2009.01059.x

DO - 10.1111/j.1600-0625.2009.01059.x

M3 - Article

C2 - 20158518

VL - 19

SP - 313

EP - 324

JO - Experimental Dermatology

JF - Experimental Dermatology

SN - 1600-0625

IS - 4

ER -