Evaluation of Prognostic and Predictive Models in the Oncology Clinic

Research output: Contribution to journalArticlepeer-review

  • External authors:
  • M. Craddock
  • C. Crockett
  • S.N. van der Veer

Abstract

Predictive and prognostic models hold great potential to support clinical decision making in oncology and could ultimately facilitate a paradigm shift to a more personalised form of treatment. While a large number of models relevant to the field of oncology have been developed, few have been translated into clinical use and assessment of clinical utility is not currently considered a routine part of model development. In this narrative review of the clinical evaluation of prediction models in oncology, we propose a high-level process diagram for the life cycle of a clinical model, encompassing model commissioning, clinical implementation and ongoing quality assurance, which aims to bridge the gap between model development and clinical implementation.

Bibliographical metadata

Original languageEnglish
Pages (from-to)102-113
Number of pages12
JournalClinical Oncology
Volume34
Issue number2
Early online date15 Dec 2021
DOIs
Publication statusPublished - Feb 2022