Enhancing fraction measured using dynamic contrast-enhanced MRI predicts disease-free survival in patients with carcinoma of the cervixCitation formats

  • External authors:
  • S. B. Donaldson
  • D. L. Buckley
  • S. E. Davidson
  • B. M. Carrington
  • A. P. Jones

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Enhancing fraction measured using dynamic contrast-enhanced MRI predicts disease-free survival in patients with carcinoma of the cervix. / Donaldson, S. B.; Buckley, D. L.; O'Connor, J. P.; Davidson, S. E.; Carrington, B. M.; Jones, A. P.; West, C. M L.

In: British Journal of Cancer, Vol. 102, No. 1, 01.2010, p. 23-26.

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Donaldson, SB, Buckley, DL, O'Connor, JP, Davidson, SE, Carrington, BM, Jones, AP & West, CML 2010, 'Enhancing fraction measured using dynamic contrast-enhanced MRI predicts disease-free survival in patients with carcinoma of the cervix', British Journal of Cancer, vol. 102, no. 1, pp. 23-26. https://doi.org/10.1038/sj.bjc.6605415

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Author

Donaldson, S. B. ; Buckley, D. L. ; O'Connor, J. P. ; Davidson, S. E. ; Carrington, B. M. ; Jones, A. P. ; West, C. M L. / Enhancing fraction measured using dynamic contrast-enhanced MRI predicts disease-free survival in patients with carcinoma of the cervix. In: British Journal of Cancer. 2010 ; Vol. 102, No. 1. pp. 23-26.

Bibtex

@article{fef6d507a767470ba67d2f89d6bdebb9,
title = "Enhancing fraction measured using dynamic contrast-enhanced MRI predicts disease-free survival in patients with carcinoma of the cervix",
abstract = "Background: There is a need for simple imaging parameters capable of predicting therapeutic outcome.Methods: This retrospective study analysed 50 patients with locally advanced carcinoma of the cervix who underwent dynamic contrast-enhanced MRI before receiving potentially curative radiotherapy. The proportion of enhancing pixels (E F) in the whole-tumour volume post-contrast agent injection was calculated and assessed in relation to disease-free survival (DFS).Results: Tumours with high E F had a significantly poorer probability of DFS than those with low E F (P0.011).Interpretation:E F is a simple imaging biomarker that should be studied further in a multi-centre setting. {\textcopyright} 2010 Cancer Research UK All rights reserved.",
keywords = "Cervix cancer, Dynamic contrast-enhanced MRI, Enhancing fraction, Imaging biomarkers, Radiotherapy",
author = "Donaldson, {S. B.} and Buckley, {D. L.} and O'Connor, {J. P.} and Davidson, {S. E.} and Carrington, {B. M.} and Jones, {A. P.} and West, {C. M L}",
year = "2010",
month = jan,
doi = "10.1038/sj.bjc.6605415",
language = "English",
volume = "102",
pages = "23--26",
journal = "BJC",
issn = "0007-0920",
publisher = "Springer Nature",
number = "1",

}

RIS

TY - JOUR

T1 - Enhancing fraction measured using dynamic contrast-enhanced MRI predicts disease-free survival in patients with carcinoma of the cervix

AU - Donaldson, S. B.

AU - Buckley, D. L.

AU - O'Connor, J. P.

AU - Davidson, S. E.

AU - Carrington, B. M.

AU - Jones, A. P.

AU - West, C. M L

PY - 2010/1

Y1 - 2010/1

N2 - Background: There is a need for simple imaging parameters capable of predicting therapeutic outcome.Methods: This retrospective study analysed 50 patients with locally advanced carcinoma of the cervix who underwent dynamic contrast-enhanced MRI before receiving potentially curative radiotherapy. The proportion of enhancing pixels (E F) in the whole-tumour volume post-contrast agent injection was calculated and assessed in relation to disease-free survival (DFS).Results: Tumours with high E F had a significantly poorer probability of DFS than those with low E F (P0.011).Interpretation:E F is a simple imaging biomarker that should be studied further in a multi-centre setting. © 2010 Cancer Research UK All rights reserved.

AB - Background: There is a need for simple imaging parameters capable of predicting therapeutic outcome.Methods: This retrospective study analysed 50 patients with locally advanced carcinoma of the cervix who underwent dynamic contrast-enhanced MRI before receiving potentially curative radiotherapy. The proportion of enhancing pixels (E F) in the whole-tumour volume post-contrast agent injection was calculated and assessed in relation to disease-free survival (DFS).Results: Tumours with high E F had a significantly poorer probability of DFS than those with low E F (P0.011).Interpretation:E F is a simple imaging biomarker that should be studied further in a multi-centre setting. © 2010 Cancer Research UK All rights reserved.

KW - Cervix cancer

KW - Dynamic contrast-enhanced MRI

KW - Enhancing fraction

KW - Imaging biomarkers

KW - Radiotherapy

U2 - 10.1038/sj.bjc.6605415

DO - 10.1038/sj.bjc.6605415

M3 - Article

VL - 102

SP - 23

EP - 26

JO - BJC

JF - BJC

SN - 0007-0920

IS - 1

ER -