Enhancing fraction measured using dynamic contrast-enhanced MRI predicts disease-free survival in patients with carcinoma of the cervix
Research output: Contribution to journal › Article › peer-review
Abstract
Background: There is a need for simple imaging parameters capable of predicting therapeutic outcome.Methods: This retrospective study analysed 50 patients with locally advanced carcinoma of the cervix who underwent dynamic contrast-enhanced MRI before receiving potentially curative radiotherapy. The proportion of enhancing pixels (E F) in the whole-tumour volume post-contrast agent injection was calculated and assessed in relation to disease-free survival (DFS).Results: Tumours with high E F had a significantly poorer probability of DFS than those with low E F (P0.011).Interpretation:E F is a simple imaging biomarker that should be studied further in a multi-centre setting. © 2010 Cancer Research UK All rights reserved.
Bibliographical metadata
| Original language | English |
|---|---|
| Pages (from-to) | 23-26 |
| Number of pages | 3 |
| Journal | British Journal of Cancer |
| Volume | 102 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 2010 |