Enantioselective copper catalysed, direct functionalisation of allenes via allyl copper intermediates

Research output: Contribution to journalArticle

Abstract

The direct functionalisation of allenes under copper catalysis enables efficient access to enantioenriched, densely functionalised molecules. In this review we explore the breadth and depth of a versatile reaction manifold, which involves the element-cupration of allenes to generate allyl copper intermediates that are subsequently coupled with diverse arrays of electrophiles.

Bibliographical metadata

Original languageEnglish
Pages (from-to)5240-5247
Number of pages8
JournalChemical Science
Volume8
Early online date8 Jun 2017
DOIs
Publication statusPublished - 2017