Efficient visual object and word recognition relies on high spatial frequency coding in the left posterior fusiform gyrus: Evidence from a case-series of patients with ventral occipito-temporal cortex damageCitation formats

  • External authors:
  • Daniel J. Roberts
  • Esther Kim
  • Pelagie M. Beeson
  • Steven Z. Rapcsak

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Efficient visual object and word recognition relies on high spatial frequency coding in the left posterior fusiform gyrus: Evidence from a case-series of patients with ventral occipito-temporal cortex damage. / Roberts, Daniel J.; Woollams, Anna M.; Kim, Esther; Beeson, Pelagie M.; Rapcsak, Steven Z.; Lambon Ralph, Matthew A.

In: Cerebral Cortex, Vol. 23, No. 11, 11.2013, p. 2568-2580.

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@article{e8cab1045530497aaecd344d9de8ff14,
title = "Efficient visual object and word recognition relies on high spatial frequency coding in the left posterior fusiform gyrus: Evidence from a case-series of patients with ventral occipito-temporal cortex damage",
abstract = "Recent visual neuroscience investigations suggest that ventral occipito-temporal cortex is retinotopically organized, with high acuity foveal input projecting primarily to the posterior fusiform gyrus (pFG), making this region crucial for coding high spatial frequency information. Because high spatial frequencies are critical for fine-grained visual discrimination, we hypothesized that damage to the left pFG should have an adverse effect not only on efficient reading, as observed in pure alexia, but also on the processing of complex non-orthographic visual stimuli. Consistent with this hypothesis, we obtained evidence that a large case series (n = 20) of patients with lesions centered on left pFG: 1) Exhibited reduced sensitivity to high spatial frequencies; 2) demonstrated prolonged response latencies both in reading (pure alexia) and object naming; and 3) were especially sensitive to visual complexity and similarity when discriminating between novel visual patterns. These results suggest that the patients' dual reading and non-orthographic recognition impairments have a common underlying mechanism and reflect the loss of high spatial frequency visual information normally coded in the left pFG. {\circledC} 2012 The Author.",
keywords = "foveal/parafoveal vision, fusiform gyrus, letter-by-letter reading, pure alexia, spatial frequency, ventral occipito-temporal cortex, visual recognition",
author = "Roberts, {Daniel J.} and Woollams, {Anna M.} and Esther Kim and Beeson, {Pelagie M.} and Rapcsak, {Steven Z.} and {Lambon Ralph}, {Matthew A.}",
note = "007646, PHS HHS, United States008286, PHS HHS, United StatesG0501632, Medical Research Council, United KingdomMR/J004146/1, Medical Research Council, United KingdomR01 DC007646, NIDCD NIH HHS, United States",
year = "2013",
month = "11",
doi = "10.1093/cercor/bhs224",
language = "English",
volume = "23",
pages = "2568--2580",
journal = "Cerebral cortex (New York, N.Y. : 1991)",
issn = "1047-3211",
publisher = "Oxford University Press",
number = "11",

}

RIS

TY - JOUR

T1 - Efficient visual object and word recognition relies on high spatial frequency coding in the left posterior fusiform gyrus: Evidence from a case-series of patients with ventral occipito-temporal cortex damage

AU - Roberts, Daniel J.

AU - Woollams, Anna M.

AU - Kim, Esther

AU - Beeson, Pelagie M.

AU - Rapcsak, Steven Z.

AU - Lambon Ralph, Matthew A.

N1 - 007646, PHS HHS, United States008286, PHS HHS, United StatesG0501632, Medical Research Council, United KingdomMR/J004146/1, Medical Research Council, United KingdomR01 DC007646, NIDCD NIH HHS, United States

PY - 2013/11

Y1 - 2013/11

N2 - Recent visual neuroscience investigations suggest that ventral occipito-temporal cortex is retinotopically organized, with high acuity foveal input projecting primarily to the posterior fusiform gyrus (pFG), making this region crucial for coding high spatial frequency information. Because high spatial frequencies are critical for fine-grained visual discrimination, we hypothesized that damage to the left pFG should have an adverse effect not only on efficient reading, as observed in pure alexia, but also on the processing of complex non-orthographic visual stimuli. Consistent with this hypothesis, we obtained evidence that a large case series (n = 20) of patients with lesions centered on left pFG: 1) Exhibited reduced sensitivity to high spatial frequencies; 2) demonstrated prolonged response latencies both in reading (pure alexia) and object naming; and 3) were especially sensitive to visual complexity and similarity when discriminating between novel visual patterns. These results suggest that the patients' dual reading and non-orthographic recognition impairments have a common underlying mechanism and reflect the loss of high spatial frequency visual information normally coded in the left pFG. © 2012 The Author.

AB - Recent visual neuroscience investigations suggest that ventral occipito-temporal cortex is retinotopically organized, with high acuity foveal input projecting primarily to the posterior fusiform gyrus (pFG), making this region crucial for coding high spatial frequency information. Because high spatial frequencies are critical for fine-grained visual discrimination, we hypothesized that damage to the left pFG should have an adverse effect not only on efficient reading, as observed in pure alexia, but also on the processing of complex non-orthographic visual stimuli. Consistent with this hypothesis, we obtained evidence that a large case series (n = 20) of patients with lesions centered on left pFG: 1) Exhibited reduced sensitivity to high spatial frequencies; 2) demonstrated prolonged response latencies both in reading (pure alexia) and object naming; and 3) were especially sensitive to visual complexity and similarity when discriminating between novel visual patterns. These results suggest that the patients' dual reading and non-orthographic recognition impairments have a common underlying mechanism and reflect the loss of high spatial frequency visual information normally coded in the left pFG. © 2012 The Author.

KW - foveal/parafoveal vision

KW - fusiform gyrus

KW - letter-by-letter reading

KW - pure alexia

KW - spatial frequency

KW - ventral occipito-temporal cortex

KW - visual recognition

U2 - 10.1093/cercor/bhs224

DO - 10.1093/cercor/bhs224

M3 - Article

C2 - 22923086

VL - 23

SP - 2568

EP - 2580

JO - Cerebral cortex (New York, N.Y. : 1991)

JF - Cerebral cortex (New York, N.Y. : 1991)

SN - 1047-3211

IS - 11

ER -