Effects of Knot Tightness at the Molecular LevelCitation formats

  • External authors:
  • Liang Zhang
  • Jean-Francois Lemonnier
  • Angela Acocella
  • Matteo Calvaresi
  • Francesco Zerbetto

Standard

Effects of Knot Tightness at the Molecular Level. / Zhang, Liang; Lemonnier, Jean-Francois; Acocella, Angela; Calvaresi, Matteo; Zerbetto, Francesco; Leigh, David.

In: Proceedings of the National Academy of Sciences, 2019.

Research output: Contribution to journalArticle

Harvard

Zhang, L, Lemonnier, J-F, Acocella, A, Calvaresi, M, Zerbetto, F & Leigh, D 2019, 'Effects of Knot Tightness at the Molecular Level', Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1815570116

APA

Zhang, L., Lemonnier, J-F., Acocella, A., Calvaresi, M., Zerbetto, F., & Leigh, D. (2019). Effects of Knot Tightness at the Molecular Level. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1815570116

Vancouver

Zhang L, Lemonnier J-F, Acocella A, Calvaresi M, Zerbetto F, Leigh D. Effects of Knot Tightness at the Molecular Level. Proceedings of the National Academy of Sciences. 2019. https://doi.org/10.1073/pnas.1815570116

Author

Zhang, Liang ; Lemonnier, Jean-Francois ; Acocella, Angela ; Calvaresi, Matteo ; Zerbetto, Francesco ; Leigh, David. / Effects of Knot Tightness at the Molecular Level. In: Proceedings of the National Academy of Sciences. 2019.

Bibtex

@article{b67a0243c0174a4899dda83cc0317da0,
title = "Effects of Knot Tightness at the Molecular Level",
abstract = "Three 819 knots in closed-loop strands of different lengths (approximately 20, 23 and 26 nm) were used to experimentally assess the consequences of knot tightness at the molecular level. Through the use of 1H nuclear magnetic resonance (NMR), diffusion ordered spectroscopy (DOSY), circular dichroism (CD), collision induced dissociation mass spectrometry (CID-MS) and molecular dynamics (MD) simulations on the different sized knots, we find that the structure, dynamics and reactivity of the molecular chains are dramatically affected by the tightness of the knotting. The tautness of entanglement causes differences in conformation, enhances the expression of topological chirality, weakens covalent bonds, inhibits decomplexation events and changes absorption properties. Understanding the effects of tightening nanoscale knots may usefully inform the design of knotted and entangled molecular materials.",
author = "Liang Zhang and Jean-Francois Lemonnier and Angela Acocella and Matteo Calvaresi and Francesco Zerbetto and David Leigh",
year = "2019",
doi = "10.1073/pnas.1815570116",
language = "English",
journal = "Proceedings of the National Academy of Sciences",
issn = "0027-8424",
publisher = "National Academy of Sciences",

}

RIS

TY - JOUR

T1 - Effects of Knot Tightness at the Molecular Level

AU - Zhang, Liang

AU - Lemonnier, Jean-Francois

AU - Acocella, Angela

AU - Calvaresi, Matteo

AU - Zerbetto, Francesco

AU - Leigh, David

PY - 2019

Y1 - 2019

N2 - Three 819 knots in closed-loop strands of different lengths (approximately 20, 23 and 26 nm) were used to experimentally assess the consequences of knot tightness at the molecular level. Through the use of 1H nuclear magnetic resonance (NMR), diffusion ordered spectroscopy (DOSY), circular dichroism (CD), collision induced dissociation mass spectrometry (CID-MS) and molecular dynamics (MD) simulations on the different sized knots, we find that the structure, dynamics and reactivity of the molecular chains are dramatically affected by the tightness of the knotting. The tautness of entanglement causes differences in conformation, enhances the expression of topological chirality, weakens covalent bonds, inhibits decomplexation events and changes absorption properties. Understanding the effects of tightening nanoscale knots may usefully inform the design of knotted and entangled molecular materials.

AB - Three 819 knots in closed-loop strands of different lengths (approximately 20, 23 and 26 nm) were used to experimentally assess the consequences of knot tightness at the molecular level. Through the use of 1H nuclear magnetic resonance (NMR), diffusion ordered spectroscopy (DOSY), circular dichroism (CD), collision induced dissociation mass spectrometry (CID-MS) and molecular dynamics (MD) simulations on the different sized knots, we find that the structure, dynamics and reactivity of the molecular chains are dramatically affected by the tightness of the knotting. The tautness of entanglement causes differences in conformation, enhances the expression of topological chirality, weakens covalent bonds, inhibits decomplexation events and changes absorption properties. Understanding the effects of tightening nanoscale knots may usefully inform the design of knotted and entangled molecular materials.

U2 - 10.1073/pnas.1815570116

DO - 10.1073/pnas.1815570116

M3 - Article

JO - Proceedings of the National Academy of Sciences

JF - Proceedings of the National Academy of Sciences

SN - 0027-8424

ER -