Distortion correction for diffusion-weighted MRI tractography and fMRI in the temporal lobesCitation formats

  • External authors:
  • Karl V. Embleton
  • Hamied A. Haroon
  • David M. Morris

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Distortion correction for diffusion-weighted MRI tractography and fMRI in the temporal lobes. / Haroon, Hamied; Embleton, Karl V.; Haroon, Hamied A.; Morris, David M.; Ralph, Matthew A Lambon; Parker, Geoff J M.

In: Human Brain Mapping, Vol. 31, No. 10, 10.2010, p. 1570-1587.

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Haroon, Hamied ; Embleton, Karl V. ; Haroon, Hamied A. ; Morris, David M. ; Ralph, Matthew A Lambon ; Parker, Geoff J M. / Distortion correction for diffusion-weighted MRI tractography and fMRI in the temporal lobes. In: Human Brain Mapping. 2010 ; Vol. 31, No. 10. pp. 1570-1587.

Bibtex

@article{c93389d1590d4e54838938367f77d1b7,
title = "Distortion correction for diffusion-weighted MRI tractography and fMRI in the temporal lobes",
abstract = "Single shot echo-planar imaging (EPI) sequences are currently the most commonly used sequences for diffusion-weighted imaging (DWI) and functional magnetic resonance imaging (fMRI) as they allow relatively high signal to noise with rapid acquisition time. A major drawback of EPI is the substantial geometric distortion and signal loss that can occur due to magnetic field inhomogeneities close to air-tissue boundaries. If DWI-based tractography and fMRI are to be applied to these regions, then the distortions must be accurately corrected to achieve meaningful results. We describe robust acquisition and processing methods for correcting such distortions in spin echo (SE) EPI using a variant of the reversed direction k space traversal method with a number of novel additions. We demonstrate that dual direction k space traversal with maintained diffusion-encoding gradient strength and direction results in correction of the great majority of eddy current-associated distortions in DWI, in addition to those created by variations in magnetic susceptibility. We also provide examples to demonstrate that the presence of severe distortions cannot be ignored if meaningful tractography results are desired. The distortion correction routine was applied to SE-EPI fMRI acquisitions and allowed detection of activation in the temporal lobe that had been previously found using PET but not conventional fMRI. {\circledC} 2010 Wiley-Liss, Inc.",
keywords = "Diffusion-weighted imaging, Distortion, Echo planar imaging, FMRI, Magnetic susceptibility, Tractography",
author = "Hamied Haroon and Embleton, {Karl V.} and Haroon, {Hamied A.} and Morris, {David M.} and Ralph, {Matthew A Lambon} and Parker, {Geoff J M}",
note = "BB/E002226/1, Biotechnology and Biological Sciences Research Council, United KingdomG0300952, Medical Research Council, United KingdomG0501632, Medical Research Council, United Kingdom",
year = "2010",
month = "10",
doi = "10.1002/hbm.20959",
language = "English",
volume = "31",
pages = "1570--1587",
journal = "Human Brain Mapping",
issn = "1065-9471",
publisher = "John Wiley & Sons Ltd",
number = "10",

}

RIS

TY - JOUR

T1 - Distortion correction for diffusion-weighted MRI tractography and fMRI in the temporal lobes

AU - Haroon, Hamied

AU - Embleton, Karl V.

AU - Haroon, Hamied A.

AU - Morris, David M.

AU - Ralph, Matthew A Lambon

AU - Parker, Geoff J M

N1 - BB/E002226/1, Biotechnology and Biological Sciences Research Council, United KingdomG0300952, Medical Research Council, United KingdomG0501632, Medical Research Council, United Kingdom

PY - 2010/10

Y1 - 2010/10

N2 - Single shot echo-planar imaging (EPI) sequences are currently the most commonly used sequences for diffusion-weighted imaging (DWI) and functional magnetic resonance imaging (fMRI) as they allow relatively high signal to noise with rapid acquisition time. A major drawback of EPI is the substantial geometric distortion and signal loss that can occur due to magnetic field inhomogeneities close to air-tissue boundaries. If DWI-based tractography and fMRI are to be applied to these regions, then the distortions must be accurately corrected to achieve meaningful results. We describe robust acquisition and processing methods for correcting such distortions in spin echo (SE) EPI using a variant of the reversed direction k space traversal method with a number of novel additions. We demonstrate that dual direction k space traversal with maintained diffusion-encoding gradient strength and direction results in correction of the great majority of eddy current-associated distortions in DWI, in addition to those created by variations in magnetic susceptibility. We also provide examples to demonstrate that the presence of severe distortions cannot be ignored if meaningful tractography results are desired. The distortion correction routine was applied to SE-EPI fMRI acquisitions and allowed detection of activation in the temporal lobe that had been previously found using PET but not conventional fMRI. © 2010 Wiley-Liss, Inc.

AB - Single shot echo-planar imaging (EPI) sequences are currently the most commonly used sequences for diffusion-weighted imaging (DWI) and functional magnetic resonance imaging (fMRI) as they allow relatively high signal to noise with rapid acquisition time. A major drawback of EPI is the substantial geometric distortion and signal loss that can occur due to magnetic field inhomogeneities close to air-tissue boundaries. If DWI-based tractography and fMRI are to be applied to these regions, then the distortions must be accurately corrected to achieve meaningful results. We describe robust acquisition and processing methods for correcting such distortions in spin echo (SE) EPI using a variant of the reversed direction k space traversal method with a number of novel additions. We demonstrate that dual direction k space traversal with maintained diffusion-encoding gradient strength and direction results in correction of the great majority of eddy current-associated distortions in DWI, in addition to those created by variations in magnetic susceptibility. We also provide examples to demonstrate that the presence of severe distortions cannot be ignored if meaningful tractography results are desired. The distortion correction routine was applied to SE-EPI fMRI acquisitions and allowed detection of activation in the temporal lobe that had been previously found using PET but not conventional fMRI. © 2010 Wiley-Liss, Inc.

KW - Diffusion-weighted imaging

KW - Distortion

KW - Echo planar imaging

KW - FMRI

KW - Magnetic susceptibility

KW - Tractography

U2 - 10.1002/hbm.20959

DO - 10.1002/hbm.20959

M3 - Article

VL - 31

SP - 1570

EP - 1587

JO - Human Brain Mapping

T2 - Human Brain Mapping

JF - Human Brain Mapping

SN - 1065-9471

IS - 10

ER -