Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy

Research output: Contribution to journalArticle

  • External authors:
  • Liam Byrne
  • Peter Kiraly
  • Mohammadali Foroozandeh
  • Liladhar Paudel
  • Jonathan Clayden


An NMR method is reported that allows diastereomeric ratios to be determined even in crowded spectra or where chemical shift differences are small compared to multiplet widths. Band-selective pure shift NMR collapses multiplets to singlets, greatly improving spectral resolution while largely retaining, or even enhancing, signal-to-noise ratio. © 2014 The Royal Society of Chemistry.

Bibliographical metadata

Original languageEnglish
Pages (from-to)2512-2514
Number of pages3
JournalChemical Communications
Issue number19
StatePublished - 7 Mar 2014