Diastereomeric ratio determination by high sensitivity band-selective pure shift NMR spectroscopy

Research output: Contribution to journalArticle

  • External authors:
  • Liam Byrne
  • Peter Kiraly
  • Mohammadali Foroozandeh
  • Liladhar Paudel
  • Jonathan Clayden

Abstract

An NMR method is reported that allows diastereomeric ratios to be determined even in crowded spectra or where chemical shift differences are small compared to multiplet widths. Band-selective pure shift NMR collapses multiplets to singlets, greatly improving spectral resolution while largely retaining, or even enhancing, signal-to-noise ratio. © 2014 The Royal Society of Chemistry.

Bibliographical metadata

Original languageEnglish
Pages (from-to)2512-2514
Number of pages3
JournalChemical Communications
Volume50
Issue number19
DOIs
StatePublished - 7 Mar 2014