Decarboxylative cross-coupling of azoyl carboxylic acids with aryl halides

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Decarboxylative cross-coupling of thiazole and oxazole-5-carboxylic acids with aryl halides is reported. Under a bimetallic system of catalytic palladium and a stoichiometric silver carbonate, a variety of (hetero)arylated azoles can be prepared in excellent yield. © 2010 American Chemical Society.

Bibliographical metadata

Original languageEnglish
Pages (from-to)4745-4747
Number of pages2
JournalOrganic Letters
Issue number21
StatePublished - 5 Nov 2010