Cysteine Cathepsin Protease Inhibition: An update on its Diagnostic, Prognostic and Therapeutic Potential in Cancer

Research output: Contribution to journalReview article

  • Authors:
  • Surinder M. Soond
  • Maria V Kozhevnikova
  • Paul Townsend
  • Andrey A Zamyatnin

Abstract

In keeping with recent developments in basic research; the importance of the Cathepsins as targets in cancer therapy have taken on increasing importance and given rise to a number of key areas of interest in the clinical setting. In keeping with driving basic research in this area in a translational direction; recent findings have given rise to a number of exciting developments in the areas of cancer diagnosis; prognosis and therapeutic development. As a fast-moving area of research; the focus of this review brings together the latest findings and highlights the translational significance of these developments.

Bibliographical metadata

Original languageEnglish
Number of pages14
JournalPharmaceuticals (Basel, Switzerland)
Volume12
Issue number2
DOIs
Publication statusPublished - 11 Jun 2019