Cortical thickness, cortical and subcortical volume, and white matter integrity in patients with their first episode of major depressionCitation formats

  • External authors:
  • Kyu Man Han
  • Sunyoung Choi
  • Kyoung Sae Na
  • Ho Kyoung Yoon
  • Min Soo Lee
  • Byung Joo Ham

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Cortical thickness, cortical and subcortical volume, and white matter integrity in patients with their first episode of major depression. / Han, Kyu Man; Choi, Sunyoung; Jung, Jeyoung; Na, Kyoung Sae; Yoon, Ho Kyoung; Lee, Min Soo; Ham, Byung Joo.

In: Journal of Affective Disorders, Vol. 155, No. 1, 02.2014, p. 42-48.

Research output: Contribution to journalArticle

Harvard

APA

Han, K. M., Choi, S., Jung, J., Na, K. S., Yoon, H. K., Lee, M. S., & Ham, B. J. (2014). Cortical thickness, cortical and subcortical volume, and white matter integrity in patients with their first episode of major depression. Journal of Affective Disorders, 155(1), 42-48. https://doi.org/10.1016/j.jad.2013.10.021

Vancouver

Author

Han, Kyu Man ; Choi, Sunyoung ; Jung, Jeyoung ; Na, Kyoung Sae ; Yoon, Ho Kyoung ; Lee, Min Soo ; Ham, Byung Joo. / Cortical thickness, cortical and subcortical volume, and white matter integrity in patients with their first episode of major depression. In: Journal of Affective Disorders. 2014 ; Vol. 155, No. 1. pp. 42-48.

Bibtex

@article{e88d04c63d454b5aa1ce67ceb5d8bbd3,
title = "Cortical thickness, cortical and subcortical volume, and white matter integrity in patients with their first episode of major depression",
abstract = "Background The uncertainty over the true morphological changes in brains with major depressive disorder (MDD) underlines the necessity of comprehensive studies with multimodal structural brain imaging analyses. This study aimed to evaluate the differences in cortical thickness, cortical and subcortical volume, and white matter integrity between first episode, medication-na{\"i}ve MDD patients and healthy controls. Methods Subjects with their first episode of MDD whose illness duration had not exceeded 6 months (n=20) were enrolled in this study and were compared to age-, sex-, and education level-matched healthy controls (n=22). All participants were subjected to T1-weighted structural magnetic resonance imaging (MRI). We used an automated procedure of FreeSurfer and Tract-based spatial statistics (TBSS) to analyze differences in cortical thickness, cortical and subcortical volume, and white matter integrity between two groups. Results The patients with first episode MDD exhibited significantly reduced cortical volume in the caudal anterior cingulate gyrus (P",
keywords = "Cortical thickness, Cortical volume, Depression, First episode, Medication-na{\"i}ve, Subcortical volume",
author = "Han, {Kyu Man} and Sunyoung Choi and Jeyoung Jung and Na, {Kyoung Sae} and Yoon, {Ho Kyoung} and Lee, {Min Soo} and Ham, {Byung Joo}",
year = "2014",
month = "2",
doi = "10.1016/j.jad.2013.10.021",
language = "English",
volume = "155",
pages = "42--48",
journal = "Journal of Affective Disorders",
issn = "0165-0327",
publisher = "Elsevier BV",
number = "1",

}

RIS

TY - JOUR

T1 - Cortical thickness, cortical and subcortical volume, and white matter integrity in patients with their first episode of major depression

AU - Han, Kyu Man

AU - Choi, Sunyoung

AU - Jung, Jeyoung

AU - Na, Kyoung Sae

AU - Yoon, Ho Kyoung

AU - Lee, Min Soo

AU - Ham, Byung Joo

PY - 2014/2

Y1 - 2014/2

N2 - Background The uncertainty over the true morphological changes in brains with major depressive disorder (MDD) underlines the necessity of comprehensive studies with multimodal structural brain imaging analyses. This study aimed to evaluate the differences in cortical thickness, cortical and subcortical volume, and white matter integrity between first episode, medication-naïve MDD patients and healthy controls. Methods Subjects with their first episode of MDD whose illness duration had not exceeded 6 months (n=20) were enrolled in this study and were compared to age-, sex-, and education level-matched healthy controls (n=22). All participants were subjected to T1-weighted structural magnetic resonance imaging (MRI). We used an automated procedure of FreeSurfer and Tract-based spatial statistics (TBSS) to analyze differences in cortical thickness, cortical and subcortical volume, and white matter integrity between two groups. Results The patients with first episode MDD exhibited significantly reduced cortical volume in the caudal anterior cingulate gyrus (P

AB - Background The uncertainty over the true morphological changes in brains with major depressive disorder (MDD) underlines the necessity of comprehensive studies with multimodal structural brain imaging analyses. This study aimed to evaluate the differences in cortical thickness, cortical and subcortical volume, and white matter integrity between first episode, medication-naïve MDD patients and healthy controls. Methods Subjects with their first episode of MDD whose illness duration had not exceeded 6 months (n=20) were enrolled in this study and were compared to age-, sex-, and education level-matched healthy controls (n=22). All participants were subjected to T1-weighted structural magnetic resonance imaging (MRI). We used an automated procedure of FreeSurfer and Tract-based spatial statistics (TBSS) to analyze differences in cortical thickness, cortical and subcortical volume, and white matter integrity between two groups. Results The patients with first episode MDD exhibited significantly reduced cortical volume in the caudal anterior cingulate gyrus (P

KW - Cortical thickness

KW - Cortical volume

KW - Depression

KW - First episode

KW - Medication-naïve

KW - Subcortical volume

U2 - 10.1016/j.jad.2013.10.021

DO - 10.1016/j.jad.2013.10.021

M3 - Article

VL - 155

SP - 42

EP - 48

JO - Journal of Affective Disorders

JF - Journal of Affective Disorders

SN - 0165-0327

IS - 1

ER -