Copper-catalyzed borylative multi-component synthesis of quaternary α-amino esters

Research output: Contribution to journalArticle


Copper-catalyzed coupling of readily available ketiminoesters, allenes and a diboron affords densely functionalized
quaternary α-amino esters bearing adjacent stereocenters and versatile vinyl boronate motifs. The method utilizes a commercially
available copper(I) catalyst, operates at ambient temperature and features a catalytic allyl cupration of ketiminoesters.

Bibliographical metadata

Original languageEnglish
JournalACS Catalysis
Early online date9 Jan 2019
Publication statusPublished - 2019