COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access

Research output: Research - peer-reviewArticle

  • External authors:
  • Reza M. Salek
  • Steffen Neumann
  • Daniel Schober
  • Jan Hummel
  • Kenny Billiau
  • Joachim Kopka
  • Elon Correa
  • Theo Reijmers
  • Antonio Rosato
  • Leonardo Tenori
  • Paola Turano
  • Silvia Marin
  • Catherine Deborde
  • Daniel Jacob
  • Dominique Rolin
  • Benjamin Dartigues
  • Pablo Conesa
  • Kenneth Haug
  • Philippe Rocca-Serra
  • Steve O’Hagan
  • Jie Hao
  • Michael van Vliet
  • Marko Sysi-Aho
  • Christian Ludwig
  • Jildau Bouwman
  • Marta Cascante
  • Timothy Ebbels
  • Julian L. Griffin
  • Annick Moing
  • Macha Nikolski
  • Matej Oresic
  • Susanna Assunta Sansone
  • Mark R. Viant
  • Ulrich L. Günther
  • Thomas Hankemeier
  • Claudio Luchinat
  • Dirk Walther
  • Christoph Steinbeck

Abstract

Metabolomics has become a crucial phenotyping technique in a range of research fields including medicine, the life sciences, biotechnology and the environmental sciences. This necessitates the transfer of experimental information between research groups, as well as potentially to publishers and funders. After the initial efforts of the metabolomics standards initiative, minimum reporting standards were proposed which included the concepts for metabolomics databases. Built by the community, standards and infrastructure for metabolomics are still needed to allow storage, exchange, comparison and re-utilization of metabolomics data. The Framework Programme 7 EU Initiative ‘coordination of standards in metabolomics’ (COSMOS) is developing a robust data infrastructure and exchange standards for metabolomics data and metadata. This is to support workflows for a broad range of metabolomics applications within the European metabolomics community and the wider metabolomics and biomedical communities’ participation. Here we announce our concepts and efforts asking for re-engagement of the metabolomics community, academics and industry, journal publishers, software and hardware vendors, as well as those interested in standardisation worldwide (addressing missing metabolomics ontologies, complex-metadata capturing and XML based open source data exchange format), to join and work towards updating and implementing metabolomics standards.

Bibliographical metadata

Original languageEnglish
Pages (from-to)1587-1597
Number of pages11
JournalMetabolomics
Volume11
Issue number6
DOIs
StatePublished - 26 May 2015