Co-crystallization in the caffeine/maleic acid system: Lessons from phase equilibria

Research output: Contribution to journalArticle

  • Authors:
  • Kun Guo
  • Ghazala Sadiq
  • Colin Seaton
  • Roger Davey
  • Qiuxiang Yin


Previous studies of the cocrystallizing system caffeine - maleic acid has shown the existence of 1:1 and 2:1 cocrystals together with a new polymorph of maleic acid. In this current work, we have attempted to rationalize this behavior through measurement of the binary and ternary phase diagrams. © 2009 American Chemical Society.

Bibliographical metadata

Original languageEnglish
Pages (from-to)268-273
Number of pages5
JournalCrystal Growth and Design
Issue number1
Publication statusPublished - 6 Jan 2010