Clostridium difficile, atopy and wheeze during the first year of life

Research output: Contribution to journalArticle

  • External authors:
  • Ashley Woodcock
  • Mohammad Moradi
  • Frazer I. Smillie
  • James P. Burnie
  • Adnan Custovic


Differences have been suggested to occur in the composition of intestinal microflora from allergic and non-allergic children. In this study we used a semi-quantitative enzyme-linked immunosorbent assay (ELISA) for the measurement of Clostridium difficile-specific immunoglobulin G (IgG) (CDIgG). CDIgG was excellent in differentiating between adults with or without Cl. difficile colitis (absorbance levels, positive vs. negative controls: geometric mean (GM) 0.301, 95% CI: 0.289-0.314 vs. GM 0.167, 95% CI: 0.155-0.181; mean difference 1.8-fold, 95% CI: 1.65-1.95; p

Bibliographical metadata

Original languageEnglish
Pages (from-to)357-360
Number of pages3
JournalPediatric Allergy and Immunology
Issue number5
Publication statusPublished - Oct 2002