This commentary explores the role of climate information services in supporting the achievement of the 2030 Agenda for Sustainable Development. At the centre of the commentary is a discussion of how integrated knowledge systems are critical in the formulation of high quality climate information services towards the successful achievement of the Sustainable Development Goals (SDGs). The paper drives home two major points. Firstly, that a climate service built on integrated knowledge systems will be better positioned to match user needs in terms of skill, scale and lead time. Secondly, that integrating diverse knowledge systems for effective climate information services in the context of the 2030 Agenda for Sustainable Development will present an auspicious platform for ‘leaving no one behind’ in contributing ideas towards the achievement of the targets outlined under the 17 SDGs, contributing to the inclusive approach at the centre of Agenda 2030. The commentary also advances the idea that climate information services built upon integrated knowledge systems present opportunities for more adequately addressing the needs of the global poor, including informing agricultural decision-making in rural communities to reduce malnutrition, facilitate disaster preparedness, and tackle human diseases linked to climate change - from cardiovascular deaths and respiratory illnesses, to altered transmission of infectious diseases.