Childhood Adversity and Borderline Personality DisorderCitation formats
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Childhood Adversity and Borderline Personality Disorder : A Meta-Analysis. / Porter, Carly; Palmier-Claus, Jasper; Branitsky, Alison; Mansell, Warren; Warwick, Helen; Varese, Filippo.
In: Acta Psychiatrica Scandinavica, Vol. 141, No. 1, 01.01.2020, p. 6-20.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Childhood Adversity and Borderline Personality Disorder
T2 - A Meta-Analysis
AU - Porter, Carly
AU - Palmier-Claus, Jasper
AU - Branitsky, Alison
AU - Mansell, Warren
AU - Warwick, Helen
AU - Varese, Filippo
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Objective: The aim of this meta-analysis was to better understand the magnitude and consistency of the association between childhood adversity and borderline personality disorder (BPD) across case-control, epidemiological and prospective cohort studies. Method: Following the review protocol (reference: CRD42017075179), search terms pertaining to adversity and BPD, were entered into three search engines. Random effects meta-analysis synthesised the size and consistency of the effects. Results: 97 studies compared BPD to non-clinical (k = 40) and clinical (k = 70) controls. Meta-analysis of case control studies indicated that individuals with BPD are 13.91 (95% CI 11.11-17.43) times more likely to report childhood adversity than non-clinical controls. This effect was smaller when considering retrospective cohort (OR: 2.59; 95% CI .93-7.30) and epidemiological (OR: 2.56, 95% CI 1.24-5.30) studies. Findings were significant across adversity subtypes with emotional abuse (OR: 38.11, 95% CI: 25.99-55.88) and neglect (OR: 17.73, 95% CI=13.01-24.17) demonstrating the largest effects. Individuals with BPD were 3.15 (95% CI 2.62-3.79) times more likely to report childhood adversity than other psychiatric groups. Conclusions: This meta-analysis corroborates theoretical proposals that exposure to adverse life experiences is associated with BPD. It highlights the importance of considering childhood adversity when treating people diagnosed with BPD.
AB - Objective: The aim of this meta-analysis was to better understand the magnitude and consistency of the association between childhood adversity and borderline personality disorder (BPD) across case-control, epidemiological and prospective cohort studies. Method: Following the review protocol (reference: CRD42017075179), search terms pertaining to adversity and BPD, were entered into three search engines. Random effects meta-analysis synthesised the size and consistency of the effects. Results: 97 studies compared BPD to non-clinical (k = 40) and clinical (k = 70) controls. Meta-analysis of case control studies indicated that individuals with BPD are 13.91 (95% CI 11.11-17.43) times more likely to report childhood adversity than non-clinical controls. This effect was smaller when considering retrospective cohort (OR: 2.59; 95% CI .93-7.30) and epidemiological (OR: 2.56, 95% CI 1.24-5.30) studies. Findings were significant across adversity subtypes with emotional abuse (OR: 38.11, 95% CI: 25.99-55.88) and neglect (OR: 17.73, 95% CI=13.01-24.17) demonstrating the largest effects. Individuals with BPD were 3.15 (95% CI 2.62-3.79) times more likely to report childhood adversity than other psychiatric groups. Conclusions: This meta-analysis corroborates theoretical proposals that exposure to adverse life experiences is associated with BPD. It highlights the importance of considering childhood adversity when treating people diagnosed with BPD.
KW - borderline personality disorder
KW - adversity
KW - trauma
KW - Meta-analysis
U2 - 10.1111/acps.13118
DO - 10.1111/acps.13118
M3 - Article
VL - 141
SP - 6
EP - 20
JO - Acta Psychiatrica Scandinavica
JF - Acta Psychiatrica Scandinavica
SN - 0001-690X
IS - 1
ER -