C–H Functionalisation of Heteroaromatic Compounds via Gold Catalysis

Research output: Chapter in Book/Report/Conference proceedingChapter


In this chapter, examples of the C–H functionalisation of heteroarenes using Au catalysis are presented. The majority of examples to date describe the hydroheteroarylation of multiple bonds or Friedel–Crafts-type substitution reactions with heteroaromatic nucleophiles. These reactions are redox neutral and take advantage of the Lewis acidity of Au complexes. The reactivity of [Au(I)] and [Au(III)] in C–H activation of heteroaromatics is also discussed, and examples where this mode of reactivity has been used in oxidative couplings as well as redox-neutral reactions for the functionalisation of heteroarene C–H bonds are presented.

Bibliographical metadata

Original languageEnglish
Title of host publicationTopics in Heterocyclic Chemistry
Number of pages52
Publication statusPublished - 3 Feb 2016

Publication series

Name Topics in Heterocyclic Chemistry