Catalytic, PMe3-mediated conversion of secondary nitroalkanes to ketones: a very mild Nef-type process

Research output: Contribution to journalArticle

Abstract

Aliph. secondary nitro compds. are converted to ketones at room temp., usually in 90-100% yields, by a one-pot reaction with 220-250 mol% of trimethylphosphine (PMe3) and 50-100 mol% of tBuC6H4SSC6H4 tBu or PhthN-SePh, or 20 mol% of both additives. Thus, very mild catalytic variants of the reductive Nef-like reactions are disclosed. [on SciFinder(R)]

Bibliographical metadata

Original languageEnglish
Pages (from-to)441-444
Number of pages4
JournalTetrahedron Letters
Volume49
DOIs
Publication statusPublished - 2008