Catalytic Asymmetric C-H Arylation of (η6-Arene)Chromium Complexes: Facile Access to Planar-Chiral Phosphines

Research output: Contribution to journalArticle

  • Authors:
  • Maria Batuecas
  • Junfei Luo
  • Ivana Gergelitsova
  • Katrina Kraemer
  • Daniel Whitaker
  • And 2 others
  • External authors:
  • Inigo J. Vitorica-yrezabal
  • Igor Larrosa

Abstract

The first catalytic asymmetric direct C-H arylation of (n6-arene)-chromium complexes to obtain planar-chiral compounds is report-ed. The use of the hemilabile ligand H8-BINAP(O) is key to providing high enantioselectivity in this transformation. We show that this methodology opens the door to the synthesis of a variety of planar-chiral chromium derivatives which can be easily transformed into planar chiral mono- or diphosphines. Mechanistic studies, including synthesis and characterization of Pd and Ag complexes and their detection in the reaction mixture suggest a Pd-catalyzed/Ag-promoted catalytic system where Ag carries out the C–H activation step.

Bibliographical metadata

Original languageEnglish
JournalACS Catalysis
Early online date25 Apr 2019
DOIs
Publication statusPublished - 2019