Carboxylation of Phenols with CO2 at Atmospheric Pressure

Research output: Contribution to journalArticle

  • Authors:
  • Junfei Luo
  • Sara Preciado
  • Pan Xie
  • Igor Larrosa


A convenient and efficient method for the ortho-carboxylation of phenols under atmospheric CO2 pressure has been developed. This method provides an alternative to the previously reported Kolbe-Schmitt method, which requires very high pressures of CO2. The addition of a trisubstituted phenol has proved essential for the successful carboxylation of phenols with CO2 at standard atmospheric pressure, allowing the efficient preparation of a broad variety of salicylic acids.

Bibliographical metadata

Original languageEnglish
Pages (from-to)6798-6802
Number of pages5
JournalChemistry - A European Journal
Issue number20
StatePublished - 10 May 2016